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The Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human Primates.
Krivokrysenko VI, Toshkov IA, Gleiberman AS, Krasnov P, Shyshynova I, Bespalov I, Maitra RK, Narizhneva NV, Singh VK, Whitnall MH, Purmal AA, Shakhov AN, Gudkov AV, Feinstein E. Krivokrysenko VI, et al. Among authors: shakhov an. PLoS One. 2015 Sep 14;10(9):e0135388. doi: 10.1371/journal.pone.0135388. eCollection 2015. PLoS One. 2015. PMID: 26367124 Free PMC article.
Prevention and mitigation of acute radiation syndrome in mice by synthetic lipopeptide agonists of Toll-like receptor 2 (TLR2).
Shakhov AN, Singh VK, Bone F, Cheney A, Kononov Y, Krasnov P, Bratanova-Toshkova TK, Shakhova VV, Young J, Weil MM, Panoskaltsis-Mortari A, Orschell CM, Baker PS, Gudkov A, Feinstein E. Shakhov AN, et al. PLoS One. 2012;7(3):e33044. doi: 10.1371/journal.pone.0033044. Epub 2012 Mar 27. PLoS One. 2012. PMID: 22479357 Free PMC article.
Identification of granulocyte colony-stimulating factor and interleukin-6 as candidate biomarkers of CBLB502 efficacy as a medical radiation countermeasure.
Krivokrysenko VI, Shakhov AN, Singh VK, Bone F, Kononov Y, Shyshynova I, Cheney A, Maitra RK, Purmal A, Whitnall MH, Gudkov AV, Feinstein E. Krivokrysenko VI, et al. Among authors: shakhov an. J Pharmacol Exp Ther. 2012 Nov;343(2):497-508. doi: 10.1124/jpet.112.196071. Epub 2012 Jul 26. J Pharmacol Exp Ther. 2012. PMID: 22837010 Free PMC article.
Resistance of bone marrow stroma to genotoxic preconditioning is determined by p53.
Fedtsova N, Komarova EA, Greene KF, Novototskaya LR, Molodtsov I, Brackett CM, Strom E, Gleiberman AS, Shakhov AN, Gudkov AV. Fedtsova N, et al. Among authors: shakhov an. Cell Death Dis. 2021 May 26;12(6):545. doi: 10.1038/s41419-021-03824-3. Cell Death Dis. 2021. PMID: 34039962 Free PMC article.
Accelerated thymic atrophy as a result of elevated homeostatic expression of the genes encoded by the TNF/lymphotoxin cytokine locus.
Liepinsh DJ, Kruglov AA, Galimov AR, Shakhov AN, Shebzukhov YV, Kuchmiy AA, Grivennikov SI, Tumanov AV, Drutskaya MS, Feigenbaum L, Kuprash DV, Nedospasov SA. Liepinsh DJ, et al. Among authors: shakhov an. Eur J Immunol. 2009 Oct;39(10):2906-15. doi: 10.1002/eji.200839191. Eur J Immunol. 2009. PMID: 19735075 Free article.
Redundancy in tumor necrosis factor (TNF) and lymphotoxin (LT) signaling in vivo: mice with inactivation of the entire TNF/LT locus versus single-knockout mice.
Kuprash DV, Alimzhanov MB, Tumanov AV, Grivennikov SI, Shakhov AN, Drutskaya LN, Marino MW, Turetskaya RL, Anderson AO, Rajewsky K, Pfeffer K, Nedospasov SA. Kuprash DV, et al. Among authors: shakhov an. Mol Cell Biol. 2002 Dec;22(24):8626-34. doi: 10.1128/MCB.22.24.8626-8634.2002. Mol Cell Biol. 2002. PMID: 12446781 Free PMC article.
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