Ohsumi J - Search Results

1

Substituents at the naphthalene C3 position of (-)-Cercosporamide derivatives significantly affect the maximal efficacy as PPARγ partial agonists.

Furukawa A, Arita T, Fukuzaki T, Satoh S, Mori M, Honda T, Matsui Y, Wakabayashi K, Hayashi S, Araki K, Ohsumi J. Furukawa A, et al. Among authors: ohsumi j. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1348-51. doi: 10.1016/j.bmcl.2011.12.066. Epub 2011 Dec 16. Bioorg Med Chem Lett. 2012. PMID: 22225641

2

(-)-Cercosporamide derivatives as novel antihyperglycemic agents.

Furukawa A, Arita T, Satoh S, Araki K, Kuroha M, Ohsumi J. Furukawa A, et al. Among authors: ohsumi j. Bioorg Med Chem Lett. 2009 Feb 1;19(3):724-6. doi: 10.1016/j.bmcl.2008.12.035. Epub 2008 Dec 11. Bioorg Med Chem Lett. 2009. PMID: 19109017

3

Discovery of a novel selective PPARgamma modulator from (-)-Cercosporamide derivatives.

Furukawa A, Arita T, Satoh S, Wakabayashi K, Hayashi S, Matsui Y, Araki K, Kuroha M, Ohsumi J. Furukawa A, et al. Among authors: ohsumi j. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2095-8. doi: 10.1016/j.bmcl.2010.02.073. Epub 2010 Feb 20. Bioorg Med Chem Lett. 2010. PMID: 20219371

4

Synthesis and biological evaluation of novel (-)-Cercosporamide derivatives as potent selective PPARγ modulators.

Furukawa A, Arita T, Fukuzaki T, Mori M, Honda T, Satoh S, Matsui Y, Wakabayashi K, Hayashi S, Nakamura K, Araki K, Kuroha M, Tanaka J, Wakimoto S, Suzuki O, Ohsumi J. Furukawa A, et al. Among authors: ohsumi j. Eur J Med Chem. 2012 Aug;54:522-33. doi: 10.1016/j.ejmech.2012.05.040. Epub 2012 Jun 7. Eur J Med Chem. 2012. PMID: 22727448

5

Discovery of DS-6930, a potent selective PPARγ modulator. Part II: Lead optimization.

Shinozuka T, Tsukada T, Fujii K, Tokumaru E, Shimada K, Onishi Y, Matsui Y, Wakimoto S, Kuroha M, Ogata T, Araki K, Ohsumi J, Sawamura R, Watanabe N, Yamamoto H, Fujimoto K, Tani Y, Mori M, Tanaka J. Shinozuka T, et al. Among authors: ohsumi j. Bioorg Med Chem. 2018 Oct 1;26(18):5099-5117. doi: 10.1016/j.bmc.2018.09.005. Epub 2018 Sep 8. Bioorg Med Chem. 2018. PMID: 30220602

6

Discovery of DS-6930, a potent selective PPARγ modulator. Part I: Lead identification.

Shinozuka T, Tsukada T, Fujii K, Tokumaru E, Shimada K, Onishi Y, Matsui Y, Wakimoto S, Kuroha M, Ogata T, Araki K, Ohsumi J, Sawamura R, Watanabe N, Yamamoto H, Fujimoto K, Tani Y, Mori M, Tanaka J. Shinozuka T, et al. Among authors: ohsumi j. Bioorg Med Chem. 2018 Oct 1;26(18):5079-5098. doi: 10.1016/j.bmc.2018.09.006. Epub 2018 Sep 8. Bioorg Med Chem. 2018. PMID: 30241907

7

Pharmacology and in vitro profiling of a novel peroxisome proliferator-activated receptor γ ligand, Cerco-A.

Wakabayashi K, Hayashi S, Matsui Y, Matsumoto T, Furukawa A, Kuroha M, Tanaka N, Inaba T, Kanda S, Tanaka J, Okuyama R, Wakimoto S, Ogata T, Araki K, Ohsumi J. Wakabayashi K, et al. Among authors: ohsumi j. Biol Pharm Bull. 2011;34(7):1094-104. doi: 10.1248/bpb.34.1094. Biol Pharm Bull. 2011. PMID: 21720019 Free article.

8

Potent antidiabetic effects of rivoglitazone, a novel peroxisome proliferator-activated receptor-gamma agonist, in obese diabetic rodent models.

Kanda S, Nakashima R, Takahashi K, Tanaka J, Ogawa J, Ogata T, Yachi M, Araki K, Ohsumi J. Kanda S, et al. Among authors: ohsumi j. J Pharmacol Sci. 2009 Oct;111(2):155-66. doi: 10.1254/jphs.09084fp. Epub 2009 Oct 6. J Pharmacol Sci. 2009. PMID: 19809220 Free article.

9

Identification of molecular target of AMP-activated protein kinase activator by affinity purification and mass spectrometry.

Kosaka T, Okuyama R, Sun W, Ogata T, Harada J, Araki K, Izumi M, Yoshida T, Okuno A, Fujiwara T, Ohsumi J, Ichikawa K. Kosaka T, et al. Among authors: ohsumi j. Anal Chem. 2005 Apr 1;77(7):2050-5. doi: 10.1021/ac0484631. Anal Chem. 2005. PMID: 15801737

10

Novel benzoylpiperidine-based stearoyl-CoA desaturase-1 inhibitors: Identification of 6-[4-(2-methylbenzoyl)piperidin-1-yl]pyridazine-3-carboxylic acid (2-hydroxy-2-pyridin-3-ylethyl)amide and its plasma triglyceride-lowering effects in Zucker fatty rats.

Uto Y, Ogata T, Kiyotsuka Y, Ueno Y, Miyazawa Y, Kurata H, Deguchi T, Watanabe N, Konishi M, Okuyama R, Kurikawa N, Takagi T, Wakimoto S, Ohsumi J. Uto Y, et al. Among authors: ohsumi j. Bioorg Med Chem Lett. 2010 Jan 1;20(1):341-5. doi: 10.1016/j.bmcl.2009.10.101. Epub 2009 Oct 29. Bioorg Med Chem Lett. 2010. PMID: 19926281

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