Christensen JG - Search Results

1

MET activation mediates resistance to lapatinib inhibition of HER2-amplified gastric cancer cells.

Chen CT, Kim H, Liska D, Gao S, Christensen JG, Weiser MR. Chen CT, et al. Among authors: christensen jg. Mol Cancer Ther. 2012 Mar;11(3):660-9. doi: 10.1158/1535-7163.MCT-11-0754. Epub 2012 Jan 11. Mol Cancer Ther. 2012. PMID: 22238368 Free PMC article.

2

c-Met: structure, functions and potential for therapeutic inhibition.

Ma PC, Maulik G, Christensen J, Salgia R. Ma PC, et al. Cancer Metastasis Rev. 2003 Dec;22(4):309-25. doi: 10.1023/a:1023768811842. Cancer Metastasis Rev. 2003. PMID: 12884908 Review.

3

A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase.

Sattler M, Pride YB, Ma P, Gramlich JL, Chu SC, Quinnan LA, Shirazian S, Liang C, Podar K, Christensen JG, Salgia R. Sattler M, et al. Among authors: christensen jg. Cancer Res. 2003 Sep 1;63(17):5462-9. Cancer Res. 2003. PMID: 14500382

4

Inhibition of the met receptor in mesothelioma.

Mukohara T, Civiello G, Davis IJ, Taffaro ML, Christensen J, Fisher DE, Johnson BE, Jänne PA. Mukohara T, et al. Clin Cancer Res. 2005 Nov 15;11(22):8122-30. doi: 10.1158/1078-0432.CCR-05-1191. Clin Cancer Res. 2005. PMID: 16299245

5

Inhibition of c-Met as a therapeutic strategy for esophageal adenocarcinoma.

Watson GA, Zhang X, Stang MT, Levy RM, Queiroz de Oliveira PE, Gooding WE, Christensen JG, Hughes SJ. Watson GA, et al. Among authors: christensen jg. Neoplasia. 2006 Nov;8(11):949-55. doi: 10.1593/neo.06499. Neoplasia. 2006. PMID: 17132227 Free PMC article.

6

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling.

Engelman JA, Zejnullahu K, Mitsudomi T, Song Y, Hyland C, Park JO, Lindeman N, Gale CM, Zhao X, Christensen J, Kosaka T, Holmes AJ, Rogers AM, Cappuzzo F, Mok T, Lee C, Johnson BE, Cantley LC, Jänne PA. Engelman JA, et al. Science. 2007 May 18;316(5827):1039-43. doi: 10.1126/science.1141478. Epub 2007 Apr 26. Science. 2007. PMID: 17463250

7

Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphoma.

Christensen JG, Zou HY, Arango ME, Li Q, Lee JH, McDonnell SR, Yamazaki S, Alton GR, Mroczkowski B, Los G. Christensen JG, et al. Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3314-22. doi: 10.1158/1535-7163.MCT-07-0365. Mol Cancer Ther. 2007. PMID: 18089725

8

HER kinase activation confers resistance to MET tyrosine kinase inhibition in MET oncogene-addicted gastric cancer cells.

Bachleitner-Hofmann T, Sun MY, Chen CT, Tang L, Song L, Zeng Z, Shah M, Christensen JG, Rosen N, Solit DB, Weiser MR. Bachleitner-Hofmann T, et al. Among authors: christensen jg. Mol Cancer Ther. 2008 Nov;7(11):3499-508. doi: 10.1158/1535-7163.MCT-08-0374. Epub 2008 Oct 30. Mol Cancer Ther. 2008. PMID: 18974395

9

Association of constitutively activated hepatocyte growth factor receptor (Met) with resistance to a dual EGFR/Her2 inhibitor in non-small-cell lung cancer cells.

Agarwal S, Zerillo C, Kolmakova J, Christensen JG, Harris LN, Rimm DL, Digiovanna MP, Stern DF. Agarwal S, et al. Among authors: christensen jg. Br J Cancer. 2009 Mar 24;100(6):941-9. doi: 10.1038/sj.bjc.6604937. Epub 2009 Feb 24. Br J Cancer. 2009. PMID: 19240716 Free PMC article.

10

The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma.

Seiwert TY, Jagadeeswaran R, Faoro L, Janamanchi V, Nallasura V, El Dinali M, Yala S, Kanteti R, Cohen EE, Lingen MW, Martin L, Krishnaswamy S, Klein-Szanto A, Christensen JG, Vokes EE, Salgia R. Seiwert TY, et al. Among authors: christensen jg. Cancer Res. 2009 Apr 1;69(7):3021-31. doi: 10.1158/0008-5472.CAN-08-2881. Epub 2009 Mar 24. Cancer Res. 2009. PMID: 19318576 Free PMC article.

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