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Anti-tumor effect against human cancer xenografts by a fully human monoclonal antibody to a variant 8-epitope of CD44R1 expressed on cancer stem cells.
Masuko K, Okazaki S, Satoh M, Tanaka G, Ikeda T, Torii R, Ueda E, Nakano T, Danbayashi M, Tsuruoka T, Ohno Y, Yagi H, Yabe N, Yoshida H, Tahara T, Kataoka S, Oshino T, Shindo T, Niwa S, Ishimoto T, Baba H, Hashimoto Y, Saya H, Masuko T. Masuko K, et al. Among authors: saya h. PLoS One. 2012;7(1):e29728. doi: 10.1371/journal.pone.0029728. Epub 2012 Jan 17. PLoS One. 2012. PMID: 22272243 Free PMC article.
Involvement of hyaluronan and its receptor CD44 with choroidal neovascularization.
Mochimaru H, Takahashi E, Tsukamoto N, Miyazaki J, Yaguchi T, Koto T, Kurihara T, Noda K, Ozawa Y, Ishimoto T, Kawakami Y, Tanihara H, Saya H, Ishida S, Tsubota K. Mochimaru H, et al. Among authors: saya h. Invest Ophthalmol Vis Sci. 2009 Sep;50(9):4410-5. doi: 10.1167/iovs.08-3044. Epub 2009 Apr 1. Invest Ophthalmol Vis Sci. 2009. PMID: 19339747 Free article.
Tumor necrosis factor-alpha regulates transforming growth factor-beta-dependent epithelial-mesenchymal transition by promoting hyaluronan-CD44-moesin interaction.
Takahashi E, Nagano O, Ishimoto T, Yae T, Suzuki Y, Shinoda T, Nakamura S, Niwa S, Ikeda S, Koga H, Tanihara H, Saya H. Takahashi E, et al. Among authors: saya h. J Biol Chem. 2010 Feb 5;285(6):4060-4073. doi: 10.1074/jbc.M109.056523. Epub 2009 Dec 4. J Biol Chem. 2010. PMID: 19965872 Free PMC article.
Oncogenicity of L-type amino-acid transporter 1 (LAT1) revealed by targeted gene disruption in chicken DT40 cells: LAT1 is a promising molecular target for human cancer therapy.
Ohkawa M, Ohno Y, Masuko K, Takeuchi A, Suda K, Kubo A, Kawahara R, Okazaki S, Tanaka T, Saya H, Seki M, Enomoto T, Yagi H, Hashimoto Y, Masuko T. Ohkawa M, et al. Among authors: saya h. Biochem Biophys Res Commun. 2011 Mar 25;406(4):649-55. doi: 10.1016/j.bbrc.2011.02.135. Epub 2011 Mar 1. Biochem Biophys Res Commun. 2011. PMID: 21371427
467 results