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Vitamin E is a MIF Inhibitor.
Hegde B, Vadnal P, Sanghavi J, Korde V, Kulkarni-Almeida AA, Dagia NM. Hegde B, et al. Among authors: kulkarni almeida aa. Biochem Biophys Res Commun. 2012 Feb 10;418(2):384-9. doi: 10.1016/j.bbrc.2012.01.031. Epub 2012 Jan 18. Biochem Biophys Res Commun. 2012. PMID: 22281490
A preferential p110alpha/gamma PI3K inhibitor attenuates experimental inflammation by suppressing the production of proinflammatory mediators in a NF-kappaB-dependent manner.
Dagia NM, Agarwal G, Kamath DV, Chetrapal-Kunwar A, Gupte RD, Jadhav MG, Dadarkar SS, Trivedi J, Kulkarni-Almeida AA, Kharas F, Fonseca LC, Kumar S, Bhonde MR. Dagia NM, et al. Among authors: kulkarni almeida aa. Am J Physiol Cell Physiol. 2010 Apr;298(4):C929-41. doi: 10.1152/ajpcell.00461.2009. Epub 2010 Jan 20. Am J Physiol Cell Physiol. 2010. PMID: 20089935 Free article.
Lead optimization of isocytosine-derived xanthine oxidase inhibitors.
Bajaj K, Burudkar S, Shah P, Keche A, Ghosh U, Tannu P, Khanna S, Srivastava A, Deshmukh NJ, Dixit A, Ahire Y, Damre A, Nemmani KV, Kulkarni-Almeida A, B-Rao C, Sharma R, Sivaramakrishnan H. Bajaj K, et al. Bioorg Med Chem Lett. 2013 Feb 1;23(3):834-8. doi: 10.1016/j.bmcl.2012.11.057. Epub 2012 Nov 29. Bioorg Med Chem Lett. 2013. PMID: 23265878
Novel leads from Heliotropium ovalifolium, 4,7,8-trimethoxy-naphthalene-2-carboxylic acid and 6-hydroxy-5,7-dimethoxy-naphthalene-2-carbaldehyde show specific IL-6 inhibitory activity in THP-1 cells and primary human monocytes.
Kulkarni-Almeida A, Suthar A, Goswami H, Vishwakarma R, Chauhan VS, Balakrishnan A, Sharma S. Kulkarni-Almeida A, et al. Phytomedicine. 2008 Dec;15(12):1079-86. doi: 10.1016/j.phymed.2008.04.013. Epub 2008 Jun 25. Phytomedicine. 2008. PMID: 18583119
Isocytosine-based inhibitors of xanthine oxidase: design, synthesis, SAR, PK and in vivo efficacy in rat model of hyperuricemia.
Khanna S, Burudkar S, Bajaj K, Shah P, Keche A, Ghosh U, Desai A, Srivastava A, Kulkarni-Almeida A, Deshmukh NJ, Dixit A, Brahma MK, Bahirat U, Doshi L, Nemmani KV, Tannu P, Damre A, B-Rao C, Sharma R, Sivaramakrishnan H. Khanna S, et al. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7543-6. doi: 10.1016/j.bmcl.2012.10.029. Epub 2012 Oct 13. Bioorg Med Chem Lett. 2012. PMID: 23122864
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