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Page 1
Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism.
Cavasin MA, Demos-Davies K, Horn TR, Walker LA, Lemon DD, Birdsey N, Weiser-Evans MC, Harral J, Irwin DC, Anwar A, Yeager ME, Li M, Watson PA, Nemenoff RA, Buttrick PM, Stenmark KR, McKinsey TA. Cavasin MA, et al. Among authors: irwin dc. Circ Res. 2012 Mar 2;110(5):739-48. doi: 10.1161/CIRCRESAHA.111.258426. Epub 2012 Jan 26. Circ Res. 2012. PMID: 22282194 Free PMC article.
Mice deficient in galectin-1 exhibit attenuated physiological responses to chronic hypoxia-induced pulmonary hypertension.
Case D, Irwin D, Ivester C, Harral J, Morris K, Imamura M, Roedersheimer M, Patterson A, Carr M, Hagen M, Saavedra M, Crossno J Jr, Young KA, Dempsey EC, Poirier F, West J, Majka S. Case D, et al. Am J Physiol Lung Cell Mol Physiol. 2007 Jan;292(1):L154-64. doi: 10.1152/ajplung.00192.2006. Epub 2006 Sep 1. Am J Physiol Lung Cell Mol Physiol. 2007. PMID: 16951131 Free article.
Neonatal lung side population cells demonstrate endothelial potential and are altered in response to hyperoxia-induced lung simplification.
Irwin D, Helm K, Campbell N, Imamura M, Fagan K, Harral J, Carr M, Young KA, Klemm D, Gebb S, Dempsey EC, West J, Majka S. Irwin D, et al. Am J Physiol Lung Cell Mol Physiol. 2007 Oct;293(4):L941-51. doi: 10.1152/ajplung.00054.2007. Epub 2007 Aug 10. Am J Physiol Lung Cell Mol Physiol. 2007. PMID: 17693487 Free article.
Peroxisome proliferator-activated receptor-g agonist treatment increases septation and angiogenesis and decreases airway hyperresponsiveness in a model of experimental neonatal chronic lung disease.
Takeda K, Okamoto M, de Langhe S, Dill E, Armstrong M, Reisdorf N, Irwin D, Koster M, Wilder J, Stenmark KR, West J, Klemm D, Gelfand EW, Nozik-Grayck E, Majka SM. Takeda K, et al. Anat Rec (Hoboken). 2009 Jul;292(7):1045-61. doi: 10.1002/ar.20921. Anat Rec (Hoboken). 2009. PMID: 19484746 Free PMC article.
Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension.
Lemon DD, Horn TR, Cavasin MA, Jeong MY, Haubold KW, Long CS, Irwin DC, McCune SA, Chung E, Leinwand LA, McKinsey TA. Lemon DD, et al. Among authors: irwin dc. J Mol Cell Cardiol. 2011 Jul;51(1):41-50. doi: 10.1016/j.yjmcc.2011.04.005. Epub 2011 Apr 23. J Mol Cell Cardiol. 2011. PMID: 21539845 Free PMC article.
Free hemoglobin induction of pulmonary vascular disease: evidence for an inflammatory mechanism.
Buehler PW, Baek JH, Lisk C, Connor I, Sullivan T, Kominsky D, Majka S, Stenmark KR, Nozik-Grayck E, Bonaventura J, Irwin DC. Buehler PW, et al. Among authors: irwin dc. Am J Physiol Lung Cell Mol Physiol. 2012 Aug 15;303(4):L312-26. doi: 10.1152/ajplung.00074.2012. Epub 2012 Jun 22. Am J Physiol Lung Cell Mol Physiol. 2012. PMID: 22728465 Free PMC article.
Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension.
Wojciak-Stothard B, Abdul-Salam VB, Lao KH, Tsang H, Irwin DC, Lisk C, Loomis Z, Stenmark KR, Edwards JC, Yuspa SH, Howard LS, Edwards RJ, Rhodes CJ, Gibbs JS, Wharton J, Zhao L, Wilkins MR. Wojciak-Stothard B, et al. Among authors: irwin dc. Circulation. 2014 Apr 29;129(17):1770-80. doi: 10.1161/CIRCULATIONAHA.113.006797. Epub 2014 Feb 6. Circulation. 2014. PMID: 24503951 Free PMC article.
Selective depletion of vascular EC-SOD augments chronic hypoxic pulmonary hypertension.
Nozik-Grayck E, Woods C, Taylor JM, Benninger RK, Johnson RD, Villegas LR, Stenmark KR, Harrison DG, Majka SM, Irwin D, Farrow KN. Nozik-Grayck E, et al. Am J Physiol Lung Cell Mol Physiol. 2014 Dec 1;307(11):L868-76. doi: 10.1152/ajplung.00096.2014. Epub 2014 Oct 17. Am J Physiol Lung Cell Mol Physiol. 2014. PMID: 25326578 Free PMC article.
78 results