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Toll-like receptor 5 (TLR5), IL-1β secretion, and asparagine endopeptidase are critical factors for alveolar macrophage phagocytosis and bacterial killing.
Descamps D, Le Gars M, Balloy V, Barbier D, Maschalidi S, Tohme M, Chignard M, Ramphal R, Manoury B, Sallenave JM. Descamps D, et al. Among authors: le gars m. Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1619-24. doi: 10.1073/pnas.1108464109. Epub 2012 Jan 17. Proc Natl Acad Sci U S A. 2012. PMID: 22307620 Free PMC article.
Neutrophil elastase degrades cystic fibrosis transmembrane conductance regulator via calpains and disables channel function in vitro and in vivo.
Le Gars M, Descamps D, Roussel D, Saussereau E, Guillot L, Ruffin M, Tabary O, Hong SS, Boulanger P, Paulais M, Malleret L, Belaaouaj A, Edelman A, Huerre M, Chignard M, Sallenave JM. Le Gars M, et al. Am J Respir Crit Care Med. 2013 Jan 15;187(2):170-9. doi: 10.1164/rccm.201205-0875OC. Epub 2012 Dec 6. Am J Respir Crit Care Med. 2013. PMID: 23220915
[iNKT cells: potential therapeutic targets to fight anthrax].
Le Gars M, Haustant M, Klezovich-Benard M, Paget C, Trottein F, Goossens PL, Tournier JN. Le Gars M, et al. Med Sci (Paris). 2017 May;33(5):488-490. doi: 10.1051/medsci/20173305010. Epub 2017 Jun 14. Med Sci (Paris). 2017. PMID: 28612722 Free article. French. No abstract available.
Pregnancy-Induced Alterations in NK Cell Phenotype and Function.
Le Gars M, Seiler C, Kay AW, Bayless NL, Starosvetsky E, Moore L, Shen-Orr SS, Aziz N, Khatri P, Dekker CL, Swan GE, Davis MM, Holmes S, Blish CA. Le Gars M, et al. Front Immunol. 2019 Oct 23;10:2469. doi: 10.3389/fimmu.2019.02469. eCollection 2019. Front Immunol. 2019. PMID: 31708922 Free PMC article.
Safety and immunogenicity of Ad26.COV2.S in adults: A randomised, double-blind, placebo-controlled Phase 2a dose-finding study.
Cárdenas V, Le Gars M, Truyers C, Ruiz-Guiñazú J, Struyf F, Colfer A, Bonten M, Borobia A, Reisinger EC, Kamerling IMC, Douoguih M, Sadoff J. Cárdenas V, et al. Among authors: le gars m. Vaccine. 2024 Jun 11;42(16):3536-3546. doi: 10.1016/j.vaccine.2024.04.059. Epub 2024 May 4. Vaccine. 2024. PMID: 38705804 Free article. Clinical Trial.
B cell somatic hypermutation following COVID-19 vaccination with Ad26.COV2.S.
Jacob-Dolan C, Lifton M, Powers OC, Miller J, Hachmann NP, Vu M, Surve N, Mazurek CR, Fisher JL, Rodrigues S, Patio RC, Anand T, Le Gars M, Sadoff J, Schmidt AG, Barouch DH. Jacob-Dolan C, et al. Among authors: le gars m. iScience. 2024 Apr 9;27(5):109716. doi: 10.1016/j.isci.2024.109716. eCollection 2024 May 17. iScience. 2024. PMID: 38655202 Free PMC article.
Quantifying how single dose Ad26.COV2.S vaccine efficacy depends on Spike sequence features.
Magaret CA, Li L, deCamp AC, Rolland M, Juraska M, Williamson BD, Ludwig J, Molitor C, Benkeser D, Luedtke A, Simpkins B, Heng F, Sun Y, Carpp LN, Bai H, Dearlove BL, Giorgi EE, Jongeneelen M, Brandenburg B, McCallum M, Bowen JE, Veesler D, Sadoff J, Gray GE, Roels S, Vandebosch A, Stieh DJ, Le Gars M, Vingerhoets J, Grinsztejn B, Goepfert PA, de Sousa LP, Silva MST, Casapia M, Losso MH, Little SJ, Gaur A, Bekker LG, Garrett N, Truyers C, Van Dromme I, Swann E, Marovich MA, Follmann D, Neuzil KM, Corey L, Greninger AL, Roychoudhury P, Hyrien O, Gilbert PB. Magaret CA, et al. Among authors: le gars m. Nat Commun. 2024 Mar 11;15(1):2175. doi: 10.1038/s41467-024-46536-w. Nat Commun. 2024. PMID: 38467646 Free PMC article.
33 results