Schmidt M - Search Results

1

Preclinical safety and efficacy of human CD34(+) cells transduced with lentiviral vector for the treatment of Wiskott-Aldrich syndrome.

Scaramuzza S, Biasco L, Ripamonti A, Castiello MC, Loperfido M, Draghici E, Hernandez RJ, Benedicenti F, Radrizzani M, Salomoni M, Ranzani M, Bartholomae CC, Vicenzi E, Finocchi A, Bredius R, Bosticardo M, Schmidt M, von Kalle C, Montini E, Biffi A, Roncarolo MG, Naldini L, Villa A, Aiuti A. Scaramuzza S, et al. Among authors: schmidt m. Mol Ther. 2013 Jan;21(1):175-84. doi: 10.1038/mt.2012.23. Epub 2012 Feb 28. Mol Ther. 2013. PMID: 22371846 Free PMC article.

2

Detection and direct genomic sequencing of multiple rare unknown flanking DNA in highly complex samples.

Schmidt M, Hoffmann G, Wissler M, Lemke N, Müssig A, Glimm H, Williams DA, Ragg S, Hesemann CU, von Kalle C. Schmidt M, et al. Hum Gene Ther. 2001 May 1;12(7):743-9. doi: 10.1089/104303401750148649. Hum Gene Ther. 2001. PMID: 11339891

3

Polyclonal long-term repopulating stem cell clones in a primate model.

Schmidt M, Zickler P, Hoffmann G, Haas S, Wissler M, Muessig A, Tisdale JF, Kuramoto K, Andrews RG, Wu T, Kiem HP, Dunbar CE, von Kalle C. Schmidt M, et al. Blood. 2002 Oct 15;100(8):2737-43. doi: 10.1182/blood-2002-02-0407. Blood. 2002. PMID: 12351380 Free article.

4

Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis.

Woods NB, Muessig A, Schmidt M, Flygare J, Olsson K, Salmon P, Trono D, von Kalle C, Karlsson S. Woods NB, et al. Among authors: schmidt m. Blood. 2003 Feb 15;101(4):1284-9. doi: 10.1182/blood-2002-07-2238. Epub 2002 Oct 17. Blood. 2003. PMID: 12393514 Free article.

5

Molecular evidence of lentiviral vector-mediated gene transfer into human self-renewing, multi-potent, long-term NOD/SCID repopulating hematopoietic cells.

Ailles L, Schmidt M, Santoni de Sio FR, Glimm H, Cavalieri S, Bruno S, Piacibello W, Von Kalle C, Naldini L. Ailles L, et al. Among authors: schmidt m. Mol Ther. 2002 Nov;6(5):615-26. Mol Ther. 2002. PMID: 12409260 Free article.

6

Clonality analysis after retroviral-mediated gene transfer to CD34+ cells from the cord blood of ADA-deficient SCID neonates.

Schmidt M, Carbonaro DA, Speckmann C, Wissler M, Bohnsack J, Elder M, Aronow BJ, Nolta JA, Kohn DB, von Kalle C. Schmidt M, et al. Nat Med. 2003 Apr;9(4):463-8. doi: 10.1038/nm844. Epub 2003 Mar 17. Nat Med. 2003. PMID: 12640448

7

Comparison of three retroviral vector systems for transduction of nonobese diabetic/severe combined immunodeficiency mice repopulating human CD34+ cord blood cells.

Leurs C, Jansen M, Pollok KE, Heinkelein M, Schmidt M, Wissler M, Lindemann D, Von Kalle C, Rethwilm A, Williams DA, Hanenberg H. Leurs C, et al. Among authors: schmidt m. Hum Gene Ther. 2003 Apr 10;14(6):509-19. doi: 10.1089/104303403764539305. Hum Gene Ther. 2003. PMID: 12718762

8

Methylguanine methyltransferase-mediated in vivo selection and chemoprotection of allogeneic stem cells in a large-animal model.

Neff T, Horn PA, Peterson LJ, Thomasson BM, Thompson J, Williams DA, Schmidt M, Georges GE, von Kalle C, Kiem HP. Neff T, et al. Among authors: schmidt m. J Clin Invest. 2003 Nov;112(10):1581-8. doi: 10.1172/JCI18782. J Clin Invest. 2003. PMID: 14617759 Free PMC article.

9

Chance or necessity? Insertional mutagenesis in gene therapy and its consequences.

Baum C, von Kalle C, Staal FJ, Li Z, Fehse B, Schmidt M, Weerkamp F, Karlsson S, Wagemaker G, Williams DA. Baum C, et al. Among authors: schmidt m. Mol Ther. 2004 Jan;9(1):5-13. doi: 10.1016/j.ymthe.2003.10.013. Mol Ther. 2004. PMID: 14741772 Free article. Review.

10

Long-term clinical and molecular follow-up of large animals receiving retrovirally transduced stem and progenitor cells: no progression to clonal hematopoiesis or leukemia.

Kiem HP, Sellers S, Thomasson B, Morris JC, Tisdale JF, Horn PA, Hematti P, Adler R, Kuramoto K, Calmels B, Bonifacino A, Hu J, von Kalle C, Schmidt M, Sorrentino B, Nienhuis A, Blau CA, Andrews RG, Donahue RE, Dunbar CE. Kiem HP, et al. Among authors: schmidt m. Mol Ther. 2004 Mar;9(3):389-95. doi: 10.1016/j.ymthe.2003.12.006. Mol Ther. 2004. PMID: 15006605 Free article.

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