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α2β1 integrin promotes chemoresistance against doxorubicin in cancer cells through extracellular signal-regulated kinase (ERK).
J Biol Chem. 2012 May 18;287(21):17065-17076. doi: 10.1074/jbc.M112.349365. Epub 2012 Mar 28.
J Biol Chem. 2012.
PMID: 22457358
Free PMC article.
Clinical Trial.
Collagen/β1 integrin signaling up-regulates the ABCC1/MRP-1 transporter in an ERK/MAPK-dependent manner.
El Azreq MA, Naci D, Aoudjit F.
El Azreq MA, et al. Among authors: naci d.
Mol Biol Cell. 2012 Sep;23(17):3473-84. doi: 10.1091/mbc.E12-02-0132. Epub 2012 Jul 11.
Mol Biol Cell. 2012.
PMID: 22787275
Free PMC article.
Item in Clipboard
Alpha2beta1 integrin promotes T cell survival and migration through the concomitant activation of ERK/Mcl-1 and p38 MAPK pathways.
Naci D, Aoudjit F.
Naci D, et al.
Cell Signal. 2014 Sep;26(9):2008-15. doi: 10.1016/j.cellsig.2014.05.016. Epub 2014 May 29.
Cell Signal. 2014.
PMID: 24880062
Item in Clipboard
Alpha2beta1 integrin in cancer development and chemoresistance.
Naci D, Vuori K, Aoudjit F.
Naci D, et al.
Semin Cancer Biol. 2015 Dec;35:145-53. doi: 10.1016/j.semcancer.2015.08.004. Epub 2015 Aug 20.
Semin Cancer Biol. 2015.
PMID: 26297892
Review.
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Alpha2beta1 Integrin (VLA-2) Protects Activated Human Effector T Cells From Methotrexate-Induced Apoptosis.
Abderrazak A, El Azreq MA, Naci D, Fortin PR, Aoudjit F.
Abderrazak A, et al. Among authors: naci d.
Front Immunol. 2018 Oct 15;9:2269. doi: 10.3389/fimmu.2018.02269. eCollection 2018.
Front Immunol. 2018.
PMID: 30374344
Free PMC article.
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Cell adhesion to collagen promotes leukemia resistance to doxorubicin by reducing DNA damage through the inhibition of Rac1 activation.
Naci D, Berrazouane S, Barabé F, Aoudjit F.
Naci D, et al.
Sci Rep. 2019 Dec 19;9(1):19455. doi: 10.1038/s41598-019-55934-w.
Sci Rep. 2019.
PMID: 31857649
Free PMC article.
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