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Synthesis, σ₁, σ₂-receptors binding affinity and antiproliferative action of new C1-substituted adamantanes.
Bioorg Med Chem. 2012 May 15;20(10):3323-31. doi: 10.1016/j.bmc.2012.03.038. Epub 2012 Mar 24.
Bioorg Med Chem. 2012.
PMID: 22512908
New adamantane derivatives with sigma affinity and antiproliferative activity.
Riganas S, Papanastasiou I, Foscolos GB, Tsotinis A, Dimas K, Kourafalos VN, Eleutheriades A, Moutsos VI, Khan H, Margarita P, Georgakopoulou S, Zaniou A, Theodoropoulou M, Mantelas A, Pondiki S, Vamvakides A.
Riganas S, et al. Among authors: moutsos vi.
Med Chem. 2012 Jul;8(4):569-86. doi: 10.2174/157340612801216201.
Med Chem. 2012.
PMID: 22530894
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New adamantane phenylalkylamines with σ-receptor binding affinity and anticancer activity, associated with putative antagonism of neuropathic pain.
Riganas S, Papanastasiou I, Foscolos GB, Tsotinis A, Serin G, Mirjolet JF, Dimas K, Kourafalos VN, Eleutheriades A, Moutsos VI, Khan H, Georgakopoulou S, Zaniou A, Prassa M, Theodoropoulou M, Mantelas A, Pondiki S, Vamvakides A.
Riganas S, et al. Among authors: moutsos vi.
J Med Chem. 2012 Nov 26;55(22):10241-61. doi: 10.1021/jm3013008. Epub 2012 Nov 9.
J Med Chem. 2012.
PMID: 23094992
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Stabilization of microtubules by Combretastatin D derivatives.
Couladouros EA, Li T, Moutsos VI, Pitsinos EN, Soufli IC.
Couladouros EA, et al. Among authors: moutsos vi.
Bioorg Med Chem Lett. 1999 Oct 18;9(20):2927-8. doi: 10.1016/s0960-894x(99)00503-x.
Bioorg Med Chem Lett. 1999.
PMID: 10571149
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A short and convenient chemical route to optically pure 2-methyl chromanmethanols. Total asymmetric synthesis of beta-, gamma-, and delta-tocotrienols.
Couladouros EA, Moutsos VI, Lampropoulou M, Little JL, Hyatt JA.
Couladouros EA, et al. Among authors: moutsos vi.
J Org Chem. 2007 Aug 31;72(18):6735-41. doi: 10.1021/jo0705418. Epub 2007 Aug 9.
J Org Chem. 2007.
PMID: 17685653
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Open-chain half-bastadins mimic the effects of cyclic bastadins on calcium homeostasis in cultured neurons.
Zieminska E, Lazarewicz JW, Couladouros EA, Moutsos VI, Pitsinos EN.
Zieminska E, et al. Among authors: moutsos vi.
Bioorg Med Chem Lett. 2008 Nov 1;18(21):5734-7. doi: 10.1016/j.bmcl.2008.09.080. Epub 2008 Sep 26.
Bioorg Med Chem Lett. 2008.
PMID: 18851910
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A general method for the synthesis of bastaranes and isobastaranes: first total synthesis of bastadins 5, 10, 12, 16, 20, and 21.
Couladouros EA, Pitsinos EN, Moutsos VI, Sarakinos G.
Couladouros EA, et al. Among authors: moutsos vi.
Chemistry. 2004 Dec 17;11(1):406-21. doi: 10.1002/chem.200400904.
Chemistry. 2004.
PMID: 15562403
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Synthetic bastadins modify the activity of ryanodine receptors in cultured cerebellar granule cells.
Zieminska E, Stafiej A, Pitsinos EN, Couladouros EA, Moutsos V, Kozlowska H, Toczylowska B, Lazarewicz JW.
Zieminska E, et al.
Neurosignals. 2006-2007;15(6):283-92. doi: 10.1159/000107650. Epub 2007 Aug 27.
Neurosignals. 2006.
PMID: 17726341
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