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H(2) mediates cardioprotection via involvements of K(ATP) channels and permeability transition pores of mitochondria in dogs.
Yoshida A, Asanuma H, Sasaki H, Sanada S, Yamazaki S, Asano Y, Shinozaki Y, Mori H, Shimouchi A, Sano M, Asakura M, Minamino T, Takashima S, Sugimachi M, Mochizuki N, Kitakaze M. Yoshida A, et al. Among authors: sasaki h. Cardiovasc Drugs Ther. 2012 Jun;26(3):217-26. doi: 10.1007/s10557-012-6381-5. Cardiovasc Drugs Ther. 2012. PMID: 22527618
Novel Synthesized Radical-Containing Nanoparticles Limit Infarct Size Following Ischemia and Reperfusion in Canine Hearts.
Asanuma H, Sanada S, Yoshitomi T, Sasaki H, Takahama H, Ihara M, Takahama H, Shinozaki Y, Mori H, Asakura M, Nakano A, Sugimachi M, Asano Y, Minamino T, Takashima S, Nagasaki Y, Kitakaze M. Asanuma H, et al. Among authors: sasaki h. Cardiovasc Drugs Ther. 2017 Dec;31(5-6):501-510. doi: 10.1007/s10557-017-6758-6. Cardiovasc Drugs Ther. 2017. PMID: 29101507
Prolonged transient acidosis during early reperfusion contributes to the cardioprotective effects of postconditioning.
Fujita M, Asanuma H, Hirata A, Wakeno M, Takahama H, Sasaki H, Kim J, Takashima S, Tsukamoto O, Minamino T, Shinozaki Y, Tomoike H, Hori M, Kitakaze M. Fujita M, et al. Among authors: sasaki h. Am J Physiol Heart Circ Physiol. 2007 Apr;292(4):H2004-8. doi: 10.1152/ajpheart.01051.2006. Epub 2007 Jan 5. Am J Physiol Heart Circ Physiol. 2007. PMID: 17208997 Free article.
PKA rapidly enhances proteasome assembly and activity in in vivo canine hearts.
Asai M, Tsukamoto O, Minamino T, Asanuma H, Fujita M, Asano Y, Takahama H, Sasaki H, Higo S, Asakura M, Takashima S, Hori M, Kitakaze M. Asai M, et al. Among authors: sasaki h. J Mol Cell Cardiol. 2009 Apr;46(4):452-62. doi: 10.1016/j.yjmcc.2008.11.001. Epub 2008 Nov 13. J Mol Cell Cardiol. 2009. PMID: 19059265
Prolonged targeting of ischemic/reperfused myocardium by liposomal adenosine augments cardioprotection in rats.
Takahama H, Minamino T, Asanuma H, Fujita M, Asai T, Wakeno M, Sasaki H, Kikuchi H, Hashimoto K, Oku N, Asakura M, Kim J, Takashima S, Komamura K, Sugimachi M, Mochizuki N, Kitakaze M. Takahama H, et al. Among authors: sasaki h. J Am Coll Cardiol. 2009 Feb 24;53(8):709-17. doi: 10.1016/j.jacc.2008.11.014. J Am Coll Cardiol. 2009. PMID: 19232905 Free article.
PDE5 inhibitor efficacy is estrogen dependent in female heart disease.
Sasaki H, Nagayama T, Blanton RM, Seo K, Zhang M, Zhu G, Lee DI, Bedja D, Hsu S, Tsukamoto O, Takashima S, Kitakaze M, Mendelsohn ME, Karas RH, Kass DA, Takimoto E. Sasaki H, et al. J Clin Invest. 2014 Jun;124(6):2464-71. doi: 10.1172/JCI70731. Epub 2014 May 16. J Clin Invest. 2014. PMID: 24837433 Free PMC article.
The mitochondrial regulator PGC1α is induced by cGMP-PKG signaling and mediates the protective effects of phosphodiesterase 5 inhibition in heart failure.
Zhu G, Ueda K, Hashimoto M, Zhang M, Sasaki M, Kariya T, Sasaki H, Kaludercic N, Lee DI, Bedja D, Gabrielson M, Yuan Y, Paolocci N, Blanton RM, Karas RH, Mendelsohn ME, O'Rourke B, Kass DA, Takimoto E. Zhu G, et al. Among authors: sasaki h, sasaki m. FEBS Lett. 2022 Jan;596(1):17-28. doi: 10.1002/1873-3468.14228. Epub 2021 Nov 19. FEBS Lett. 2022. PMID: 34778969 Free PMC article.
5,793 results