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Expression of MALT1 oncogene in hematopoietic stem/progenitor cells recapitulates the pathogenesis of human lymphoma in mice.
Vicente-Dueñas C, Fontán L, Gonzalez-Herrero I, Romero-Camarero I, Segura V, Aznar MA, Alonso-Escudero E, Campos-Sanchez E, Ruiz-Roca L, Barajas-Diego M, Sagardoy A, Martinez-Ferrandis JI, Abollo-Jimenez F, Bertolo C, Peñuelas I, Garcia-Criado FJ, García-Cenador MB, Tousseyn T, Agirre X, Prosper F, Garcia-Bragado F, McPhail ED, Lossos IS, Du MQ, Flores T, Hernandez-Rivas JM, Gonzalez M, Salar A, Bellosillo B, Conde E, Siebert R, Sagaert X, Cobaleda C, Sanchez-Garcia I, Martinez-Climent JA. Vicente-Dueñas C, et al. Among authors: ruiz roca l. Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):10534-9. doi: 10.1073/pnas.1204127109. Epub 2012 Jun 11. Proc Natl Acad Sci U S A. 2012. PMID: 22689981 Free PMC article.
The age of the target cell affects B-cell leukaemia malignancy.
Vicente-Dueñas C, Abollo-Jiménez F, Ruiz-Roca L, Alonso-Escudero E, Jiménez R, Cenador MB, Criado FJ, Cobaleda C, Sánchez-García I. Vicente-Dueñas C, et al. Among authors: ruiz roca l. Aging (Albany NY). 2010 Dec;2(12):908-13. doi: 10.18632/aging.100244. Aging (Albany NY). 2010. PMID: 21164221 Free PMC article.
Genetic background affects susceptibility to tumoral stem cell reprogramming.
García-Ramírez I, Ruiz-Roca L, Martín-Lorenzo A, Blanco O, García-Cenador MB, García-Criado FJ, Vicente-Dueñas C, Sánchez-García I. García-Ramírez I, et al. Among authors: ruiz roca l. Cell Cycle. 2013 Aug 1;12(15):2505-9. doi: 10.4161/cc.25544. Epub 2013 Jul 8. Cell Cycle. 2013. PMID: 23839033 Free PMC article.
Crebbp loss cooperates with Bcl2 overexpression to promote lymphoma in mice.
García-Ramírez I, Tadros S, González-Herrero I, Martín-Lorenzo A, Rodríguez-Hernández G, Moore D, Ruiz-Roca L, Blanco O, Alonso-López D, Rivas JL, Hartert K, Duval R, Klinkebiel D, Bast M, Vose J, Lunning M, Fu K, Greiner T, Rodrigues-Lima F, Jiménez R, Criado FJG, Cenador MBG, Brindle P, Vicente-Dueñas C, Alizadeh A, Sánchez-García I, Green MR. García-Ramírez I, et al. Among authors: ruiz roca l. Blood. 2017 May 11;129(19):2645-2656. doi: 10.1182/blood-2016-08-733469. Epub 2017 Mar 13. Blood. 2017. PMID: 28288979 Free PMC article.
Infection Exposure Promotes ETV6-RUNX1 Precursor B-cell Leukemia via Impaired H3K4 Demethylases.
Rodríguez-Hernández G, Hauer J, Martín-Lorenzo A, Schäfer D, Bartenhagen C, García-Ramírez I, Auer F, González-Herrero I, Ruiz-Roca L, Gombert M, Okpanyi V, Fischer U, Chen C, Dugas M, Bhatia S, Linka RM, Garcia-Suquia M, Rascón-Trincado MV, Garcia-Sanchez A, Blanco O, García-Cenador MB, García-Criado FJ, Cobaleda C, Alonso-López D, De Las Rivas J, Müschen M, Vicente-Dueñas C, Sánchez-García I, Borkhardt A. Rodríguez-Hernández G, et al. Among authors: ruiz roca l. Cancer Res. 2017 Aug 15;77(16):4365-4377. doi: 10.1158/0008-5472.CAN-17-0701. Epub 2017 Jun 19. Cancer Res. 2017. PMID: 28630052