Menendez S - Search Results

1

Akt phosphorylates the transcriptional repressor bmi1 to block its effects on the tumor-suppressing ink4a-arf locus.

Liu Y, Liu F, Yu H, Zhao X, Sashida G, Deblasio A, Harr M, She QB, Chen Z, Lin HK, Di Giandomenico S, Elf SE, Yang Y, Miyata Y, Huang G, Menendez S, Mellinghoff IK, Rosen N, Pandolfi PP, Hedvat CV, Nimer SD. Liu Y, et al. Among authors: menendez s. Sci Signal. 2012 Oct 23;5(247):ra77. doi: 10.1126/scisignal.2003199. Sci Signal. 2012. PMID: 23092893 Free PMC article.

2

The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas.

Hernando E, Charytonowicz E, Dudas ME, Menendez S, Matushansky I, Mills J, Socci ND, Behrendt N, Ma L, Maki RG, Pandolfi PP, Cordon-Cardo C. Hernando E, et al. Among authors: menendez s. Nat Med. 2007 Jun;13(6):748-53. doi: 10.1038/nm1560. Epub 2007 May 13. Nat Med. 2007. PMID: 17496901

3

Methylation of RUNX1 by PRMT1 abrogates SIN3A binding and potentiates its transcriptional activity.

Zhao X, Jankovic V, Gural A, Huang G, Pardanani A, Menendez S, Zhang J, Dunne R, Xiao A, Erdjument-Bromage H, Allis CD, Tempst P, Nimer SD. Zhao X, et al. Among authors: menendez s. Genes Dev. 2008 Mar 1;22(5):640-53. doi: 10.1101/gad.1632608. Genes Dev. 2008. PMID: 18316480 Free PMC article.

4

p53 regulates hematopoietic stem cell quiescence.

Liu Y, Elf SE, Miyata Y, Sashida G, Liu Y, Huang G, Di Giandomenico S, Lee JM, Deblasio A, Menendez S, Antipin J, Reva B, Koff A, Nimer SD. Liu Y, et al. Among authors: menendez s. Cell Stem Cell. 2009 Jan 9;4(1):37-48. doi: 10.1016/j.stem.2008.11.006. Cell Stem Cell. 2009. PMID: 19128791 Free PMC article.

5

ELF4/MEF activates MDM2 expression and blocks oncogene-induced p16 activation to promote transformation.

Sashida G, Liu Y, Elf S, Miyata Y, Ohyashiki K, Izumi M, Menendez S, Nimer SD. Sashida G, et al. Among authors: menendez s. Mol Cell Biol. 2009 Jul;29(13):3687-99. doi: 10.1128/MCB.01551-08. Epub 2009 Apr 20. Mol Cell Biol. 2009. PMID: 19380490 Free PMC article.

6

Depletion of L3MBTL1 promotes the erythroid differentiation of human hematopoietic progenitor cells: possible role in 20q- polycythemia vera.

Perna F, Gurvich N, Hoya-Arias R, Abdel-Wahab O, Levine RL, Asai T, Voza F, Menendez S, Wang L, Liu F, Zhao X, Nimer SD. Perna F, et al. Among authors: menendez s. Blood. 2010 Oct 14;116(15):2812-21. doi: 10.1182/blood-2010-02-270611. Epub 2010 Jun 28. Blood. 2010. PMID: 20585043 Free PMC article.

7

The oncogenic role of the ETS transcription factors MEF and ERG.

Sashida G, Bazzoli E, Menendez S, Liu Y, Nimer SD. Sashida G, et al. Among authors: menendez s. Cell Cycle. 2010 Sep 1;9(17):3457-9. doi: 10.4161/cc.9.17.13000. Epub 2010 Sep 13. Cell Cycle. 2010. PMID: 20814243 Free PMC article. Review.

8

L3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability.

Gurvich N, Perna F, Farina A, Voza F, Menendez S, Hurwitz J, Nimer SD. Gurvich N, et al. Among authors: menendez s. Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22552-7. doi: 10.1073/pnas.1017092108. Epub 2010 Dec 13. Proc Natl Acad Sci U S A. 2010. PMID: 21149733 Free PMC article.

9

JAK2V617F-mediated phosphorylation of PRMT5 downregulates its methyltransferase activity and promotes myeloproliferation.

Liu F, Zhao X, Perna F, Wang L, Koppikar P, Abdel-Wahab O, Harr MW, Levine RL, Xu H, Tefferi A, Deblasio A, Hatlen M, Menendez S, Nimer SD. Liu F, et al. Among authors: menendez s. Cancer Cell. 2011 Feb 15;19(2):283-94. doi: 10.1016/j.ccr.2010.12.020. Cancer Cell. 2011. PMID: 21316606 Free PMC article.

10

The mef/elf4 transcription factor fine tunes the DNA damage response.

Sashida G, Bae N, Di Giandomenico S, Asai T, Gurvich N, Bazzoli E, Liu Y, Huang G, Zhao X, Menendez S, Nimer SD. Sashida G, et al. Among authors: menendez s. Cancer Res. 2011 Jul 15;71(14):4857-65. doi: 10.1158/0008-5472.CAN-11-0455. Epub 2011 May 26. Cancer Res. 2011. PMID: 21616937 Free PMC article.

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