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Antivirulence Isoquinolone Mannosides: Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI.
Jarvis C, Han Z, Kalas V, Klein R, Pinkner JS, Ford B, Binkley J, Cusumano CK, Cusumano Z, Mydock-McGrane L, Hultgren SJ, Janetka JW. Jarvis C, et al. Among authors: ford b. ChemMedChem. 2016 Feb 17;11(4):367-73. doi: 10.1002/cmdc.201600006. Epub 2016 Jan 26. ChemMedChem. 2016. PMID: 26812660 Free PMC article.
Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate.
Phan G, Remaut H, Wang T, Allen WJ, Pirker KF, Lebedev A, Henderson NS, Geibel S, Volkan E, Yan J, Kunze MB, Pinkner JS, Ford B, Kay CW, Li H, Hultgren SJ, Thanassi DG, Waksman G. Phan G, et al. Among authors: ford b. Nature. 2011 Jun 2;474(7349):49-53. doi: 10.1038/nature10109. Nature. 2011. PMID: 21637253 Free PMC article.
803 results