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Dishevelled3 is a novel arginine methyl transferase substrate.
Bikkavilli RK, Avasarala S, Vanscoyk M, Sechler M, Kelley N, Malbon CC, Winn RA. Bikkavilli RK, et al. Among authors: sechler m. Sci Rep. 2012;2:805. doi: 10.1038/srep00805. Epub 2012 Nov 13. Sci Rep. 2012. PMID: 23150776 Free PMC article.
hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression.
Avasarala S, Van Scoyk M, Wang J, Sechler M, Vandervest K, Brzezinski C, Weekes C, Edwards MG, Arcaroli J, Davis RE, Bikkavilli RK, Winn RA. Avasarala S, et al. Among authors: sechler m. Biol Open. 2013 May 22;2(7):675-85. doi: 10.1242/bio.20134507. Print 2013 Jul 15. Biol Open. 2013. PMID: 23862015 Free PMC article.
Novel Role for γ-Catenin in the Regulation of Cancer Cell Migration via the Induction of Hepatocyte Growth Factor Activator Inhibitor Type 1 (HAI-1).
Sechler M, Borowicz S, Van Scoyk M, Avasarala S, Zerayesus S, Edwards MG, Kumar Karuppusamy Rathinam M, Zhao X, Wu PY, Tang K, Bikkavilli RK, Winn RA. Sechler M, et al. J Biol Chem. 2015 Jun 19;290(25):15610-15620. doi: 10.1074/jbc.M114.631820. Epub 2015 Apr 29. J Biol Chem. 2015. PMID: 25925948 Free PMC article.
The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth.
Parrish JK, McCann TS, Sechler M, Sobral LM, Ren W, Jones KL, Tan AC, Jedlicka P. Parrish JK, et al. Among authors: sechler m. Oncotarget. 2018 Sep 4;9(69):33110-33123. doi: 10.18632/oncotarget.26011. eCollection 2018 Sep 4. Oncotarget. 2018. PMID: 30237855 Free PMC article.
KDM5A and PHF2 positively control expression of pro-metastatic genes repressed by EWS/Fli1, and promote growth and metastatic properties in Ewing sarcoma.
McCann TS, Parrish JK, Hsieh J, Sechler M, Sobral LM, Self C, Jones KL, Goodspeed A, Costello JC, Jedlicka P. McCann TS, et al. Among authors: sechler m. Oncotarget. 2020 Oct 27;11(43):3818-3831. doi: 10.18632/oncotarget.27737. eCollection 2020 Oct 27. Oncotarget. 2020. PMID: 33196691 Free PMC article.
11 results