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Identification and characterization of a novel vitamin B12 (cobalamin) biosynthetic enzyme (CobZ) from Rhodobacter capsulatus, containing flavin, heme, and Fe-S cofactors.
McGoldrick HM, Roessner CA, Raux E, Lawrence AD, McLean KJ, Munro AW, Santabarbara S, Rigby SE, Heathcote P, Scott AI, Warren MJ. McGoldrick HM, et al. Among authors: lawrence ad. J Biol Chem. 2005 Jan 14;280(2):1086-94. doi: 10.1074/jbc.M411884200. Epub 2004 Nov 3. J Biol Chem. 2005. PMID: 15525640 Free article.
Elucidation of substrate specificity in the cobalamin (vitamin B12) biosynthetic methyltransferases. Structure and function of the C20 methyltransferase (CbiL) from Methanothermobacter thermautotrophicus.
Frank S, Deery E, Brindley AA, Leech HK, Lawrence A, Heathcote P, Schubert HL, Brocklehurst K, Rigby SE, Warren MJ, Pickersgill RW. Frank S, et al. J Biol Chem. 2007 Aug 17;282(33):23957-69. doi: 10.1074/jbc.M703827200. Epub 2007 Jun 13. J Biol Chem. 2007. PMID: 17567575 Free article.
Evolution of enzymes and pathways for the biosynthesis of cofactors.
Holliday GL, Thornton JM, Marquet A, Smith AG, Rébeillé F, Mendel R, Schubert HL, Lawrence AD, Warren MJ. Holliday GL, et al. Among authors: lawrence ad. Nat Prod Rep. 2007 Oct;24(5):972-87. doi: 10.1039/b703107f. Epub 2007 Sep 12. Nat Prod Rep. 2007. PMID: 17898893 Review.
Demonstration that CobG, the monooxygenase associated with the ring contraction process of the aerobic cobalamin (vitamin B12) biosynthetic pathway, contains an Fe-S center and a mononuclear non-heme iron center.
Schroeder S, Lawrence AD, Biedendieck R, Rose RS, Deery E, Graham RM, McLean KJ, Munro AW, Rigby SE, Warren MJ. Schroeder S, et al. Among authors: lawrence ad. J Biol Chem. 2009 Feb 20;284(8):4796-805. doi: 10.1074/jbc.M807184200. Epub 2008 Dec 8. J Biol Chem. 2009. PMID: 19068481 Free article.
147 results