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Human oncoprotein MDM2 activates the Akt signaling pathway through an interaction with the repressor element-1 silencing transcription factor conferring a survival advantage to cancer cells.
Cell Death Differ. 2013 Apr;20(4):558-66. doi: 10.1038/cdd.2012.153. Epub 2012 Dec 14.
Cell Death Differ. 2013.
PMID: 23238568
Free PMC article.
DNA replication in progenitor cells and epithelial regeneration after lung injury requires the oncoprotein MDM2.
Singh S, Vaughan CA, Rabender C, Mikkelsen R, Deb S, Palit Deb S.
Singh S, et al. Among authors: palit deb s.
JCI Insight. 2019 Oct 17;4(20):e128194. doi: 10.1172/jci.insight.128194.
JCI Insight. 2019.
PMID: 31527309
Free PMC article.
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Constitutive Activation of DNA Damage Checkpoint Signaling Contributes to Mutant p53 Accumulation via Modulation of p53 Ubiquitination.
Frum RA, Love IM, Damle PK, Mukhopadhyay ND, Palit Deb S, Deb S, Grossman SR.
Frum RA, et al. Among authors: palit deb s.
Mol Cancer Res. 2016 May;14(5):423-36. doi: 10.1158/1541-7786.MCR-15-0363. Epub 2016 Mar 10.
Mol Cancer Res. 2016.
PMID: 26965143
Free PMC article.
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Mutant p53 establishes targetable tumor dependency by promoting unscheduled replication.
Singh S, Vaughan CA, Frum RA, Grossman SR, Deb S, Palit Deb S.
Singh S, et al. Among authors: palit deb s.
J Clin Invest. 2017 May 1;127(5):1839-1855. doi: 10.1172/JCI87724. Epub 2017 Apr 10.
J Clin Invest. 2017.
PMID: 28394262
Free PMC article.
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