McGown A - Search Results

1

Early interneuron dysfunction in ALS: insights from a mutant sod1 zebrafish model.

McGown A, McDearmid JR, Panagiotaki N, Tong H, Al Mashhadi S, Redhead N, Lyon AN, Beattie CE, Shaw PJ, Ramesh TM. McGown A, et al. Ann Neurol. 2013 Feb;73(2):246-58. doi: 10.1002/ana.23780. Epub 2012 Dec 31. Ann Neurol. 2013. PMID: 23281025 Free PMC article.

2

ZNStress: a high-throughput drug screening protocol for identification of compounds modulating neuronal stress in the transgenic mutant sod1G93R zebrafish model of amyotrophic lateral sclerosis.

McGown A, Shaw DP, Ramesh T. McGown A, et al. Mol Neurodegener. 2016 Jul 26;11(1):56. doi: 10.1186/s13024-016-0122-3. Mol Neurodegener. 2016. PMID: 27460825 Free PMC article.

3

Stable transgenic C9orf72 zebrafish model key aspects of the ALS/FTD phenotype and reveal novel pathological features.

Shaw MP, Higginbottom A, McGown A, Castelli LM, James E, Hautbergue GM, Shaw PJ, Ramesh TM. Shaw MP, et al. Among authors: mcgown a. Acta Neuropathol Commun. 2018 Nov 19;6(1):125. doi: 10.1186/s40478-018-0629-7. Acta Neuropathol Commun. 2018. PMID: 30454072 Free PMC article.

4

Animal models of multiple sclerosis: From rodents to zebrafish.

Burrows DJ, McGown A, Jain SA, De Felice M, Ramesh TM, Sharrack B, Majid A. Burrows DJ, et al. Among authors: mcgown a. Mult Scler. 2019 Mar;25(3):306-324. doi: 10.1177/1352458518805246. Epub 2018 Oct 15. Mult Scler. 2019. PMID: 30319015 Review.

5

Deficiency in the mRNA export mediator Gle1 impairs Schwann cell development in the zebrafish embryo.

Seytanoglu A, Alsomali NI, Valori CF, McGown A, Kim HR, Ning K, Ramesh T, Sharrack B, Wood JD, Azzouz M. Seytanoglu A, et al. Among authors: mcgown a. Neuroscience. 2016 May 13;322:287-97. doi: 10.1016/j.neuroscience.2016.02.039. Epub 2016 Feb 24. Neuroscience. 2016. PMID: 26921650 Free article.

6

Unbiased metabolome screen leads to personalized medicine strategy for amyotrophic lateral sclerosis.

Boddy S, Islam M, Moll T, Kurz J, Burrows D, McGown A, Bhargava A, Julian TH, Harvey C, Marshall JN, Hall BP, Allen SP, Kenna KP, Sanderson E, Zhang S, Ramesh T, Snyder MP, Shaw PJ, McDermott C, Cooper-Knock J. Boddy S, et al. Among authors: mcgown a. Brain Commun. 2022 Mar 17;4(2):fcac069. doi: 10.1093/braincomms/fcac069. eCollection 2022. Brain Commun. 2022. PMID: 35441136 Free PMC article.

7

The effect of hyperglycemia on neurovascular coupling and cerebrovascular patterning in zebrafish.

Chhabria K, Plant K, Bandmann O, Wilkinson RN, Martin C, Kugler E, Armitage PA, Santoscoy PL, Cunliffe VT, Huisken J, McGown A, Ramesh T, Chico TJ, Howarth C. Chhabria K, et al. Among authors: mcgown a. J Cereb Blood Flow Metab. 2020 Feb;40(2):298-313. doi: 10.1177/0271678X18810615. Epub 2018 Nov 6. J Cereb Blood Flow Metab. 2020. PMID: 30398083 Free PMC article.

8

High-throughput drug screens for amyotrophic lateral sclerosis drug discovery.

McGown A, Stopford MJ. McGown A, et al. Expert Opin Drug Discov. 2018 Nov;13(11):1015-1025. doi: 10.1080/17460441.2018.1533953. Epub 2018 Oct 13. Expert Opin Drug Discov. 2018. PMID: 30317895 Free article. Review.

9

Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial.

RECOVERY Collaborative Group. RECOVERY Collaborative Group. Lancet Child Adolesc Health. 2024 Mar;8(3):190-200. doi: 10.1016/S2352-4642(23)00316-4. Epub 2024 Jan 22. Lancet Child Adolesc Health. 2024. PMID: 38272046 Free article. Clinical Trial.

10

Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.

RECOVERY Collaborative Group. RECOVERY Collaborative Group. Lancet Diabetes Endocrinol. 2023 Dec;11(12):905-914. doi: 10.1016/S2213-8587(23)00253-X. Epub 2023 Oct 18. Lancet Diabetes Endocrinol. 2023. PMID: 37865101 Free PMC article. Clinical Trial.

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