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Sustained PU.1 levels balance cell-cycle regulators to prevent exhaustion of adult hematopoietic stem cells.
Staber PB, Zhang P, Ye M, Welner RS, Nombela-Arrieta C, Bach C, Kerenyi M, Bartholdy BA, Zhang H, Alberich-Jordà M, Lee S, Yang H, Ng F, Zhang J, Leddin M, Silberstein LE, Hoefler G, Orkin SH, Göttgens B, Rosenbauer F, Huang G, Tenen DG. Staber PB, et al. Among authors: bach c. Mol Cell. 2013 Mar 7;49(5):934-46. doi: 10.1016/j.molcel.2013.01.007. Epub 2013 Feb 8. Mol Cell. 2013. PMID: 23395001 Free PMC article.
The Runx-PU.1 pathway preserves normal and AML/ETO9a leukemic stem cells.
Staber PB, Zhang P, Ye M, Welner RS, Levantini E, Di Ruscio A, Ebralidze AK, Bach C, Zhang H, Zhang J, Vanura K, Delwel R, Yang H, Huang G, Tenen DG. Staber PB, et al. Among authors: bach c. Blood. 2014 Oct 9;124(15):2391-9. doi: 10.1182/blood-2014-01-550855. Epub 2014 Sep 3. Blood. 2014. PMID: 25185713 Free PMC article.
C/EBPα is required for development of dendritic cell progenitors.
Welner RS, Bararia D, Amabile G, Czibere A, Benoukraf T, Bach C, Wansa KD, Ye M, Zhang H, Iino T, Hetherington CJ, Akashi K, Tenen DG. Welner RS, et al. Among authors: bach c. Blood. 2013 May 16;121(20):4073-81. doi: 10.1182/blood-2012-10-463448. Epub 2013 Apr 1. Blood. 2013. PMID: 23547051 Free PMC article.
NOTCH2 and FLT3 gene mis-splicings are common events in patients with acute myeloid leukemia (AML): new potential targets in AML.
Adamia S, Bar-Natan M, Haibe-Kains B, Pilarski PM, Bach C, Pevzner S, Calimeri T, Avet-Loiseau H, Lode L, Verselis S, Fox EA, Galinsky I, Mathews S, Dagogo-Jack I, Wadleigh M, Steensma DP, Motyckova G, Deangelo DJ, Quackenbush J, Tenen DG, Stone RM, Griffin JD. Adamia S, et al. Among authors: bach c. Blood. 2014 May 1;123(18):2816-25. doi: 10.1182/blood-2013-02-481507. Epub 2014 Feb 26. Blood. 2014. PMID: 24574459 Free PMC article.
Leukemogenic transformation by HOXA cluster genes.
Bach C, Buhl S, Mueller D, García-Cuéllar MP, Maethner E, Slany RK. Bach C, et al. Blood. 2010 Apr 8;115(14):2910-8. doi: 10.1182/blood-2009-04-216606. Epub 2010 Feb 3. Blood. 2010. PMID: 20130239 Free article.
Misguided transcriptional elongation causes mixed lineage leukemia.
Mueller D, García-Cuéllar MP, Bach C, Buhl S, Maethner E, Slany RK. Mueller D, et al. Among authors: bach c. PLoS Biol. 2009 Nov;7(11):e1000249. doi: 10.1371/journal.pbio.1000249. Epub 2009 Nov 24. PLoS Biol. 2009. PMID: 19956800 Free PMC article.
569 results