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Blockade of individual Notch ligands and receptors controls graft-versus-host disease.
Tran IT, Sandy AR, Carulli AJ, Ebens C, Chung J, Shan GT, Radojcic V, Friedman A, Gridley T, Shelton A, Reddy P, Samuelson LC, Yan M, Siebel CW, Maillard I. Tran IT, et al. Among authors: yan m. J Clin Invest. 2013 Apr;123(4):1590-604. doi: 10.1172/JCI65477. J Clin Invest. 2013. PMID: 23454750 Free PMC article.
Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands.
Chung J, Ebens CL, Perkey E, Radojcic V, Koch U, Scarpellino L, Tong A, Allen F, Wood S, Feng J, Friedman A, Granadier D, Tran IT, Chai Q, Onder L, Yan M, Reddy P, Blazar BR, Huang AY, Brennan TV, Bishop DK, Ludewig B, Siebel CW, Radtke F, Luther SA, Maillard I. Chung J, et al. Among authors: yan m. J Clin Invest. 2017 Apr 3;127(4):1574-1588. doi: 10.1172/JCI89535. Epub 2017 Mar 20. J Clin Invest. 2017. PMID: 28319044 Free PMC article.
Therapeutic antibody targeting of individual Notch receptors.
Wu Y, Cain-Hom C, Choy L, Hagenbeek TJ, de Leon GP, Chen Y, Finkle D, Venook R, Wu X, Ridgway J, Schahin-Reed D, Dow GJ, Shelton A, Stawicki S, Watts RJ, Zhang J, Choy R, Howard P, Kadyk L, Yan M, Zha J, Callahan CA, Hymowitz SG, Siebel CW. Wu Y, et al. Among authors: yan m. Nature. 2010 Apr 15;464(7291):1052-7. doi: 10.1038/nature08878. Nature. 2010. PMID: 20393564
Chronic DLL4 blockade induces vascular neoplasms.
Yan M, Callahan CA, Beyer JC, Allamneni KP, Zhang G, Ridgway JB, Niessen K, Plowman GD. Yan M, et al. Nature. 2010 Feb 11;463(7282):E6-7. doi: 10.1038/nature08751. Nature. 2010. PMID: 20147986
Notch signal strength controls cell fate in the haemogenic endothelium.
Gama-Norton L, Ferrando E, Ruiz-Herguido C, Liu Z, Guiu J, Islam AB, Lee SU, Yan M, Guidos CJ, López-Bigas N, Maeda T, Espinosa L, Kopan R, Bigas A. Gama-Norton L, et al. Among authors: yan m. Nat Commun. 2015 Oct 14;6:8510. doi: 10.1038/ncomms9510. Nat Commun. 2015. PMID: 26465397 Free PMC article.
6,663 results