Leontieva OV - Search Results

1

Recent progress in genetics of aging, senescence and longevity: focusing on cancer-related genes.

Berman AE, Leontieva OV, Natarajan V, McCubrey JA, Demidenko ZN, Nikiforov MA. Berman AE, et al. Among authors: leontieva ov. Oncotarget. 2012 Dec;3(12):1522-32. doi: 10.18632/oncotarget.889. Oncotarget. 2012. PMID: 23455653 Free PMC article. Review.

2

Dual mTORC1/C2 inhibitors suppress cellular geroconversion (a senescence program).

Leontieva OV, Demidenko ZN, Blagosklonny MV. Leontieva OV, et al. Oncotarget. 2015 Sep 15;6(27):23238-48. doi: 10.18632/oncotarget.4836. Oncotarget. 2015. PMID: 26177051 Free PMC article.

3

Contact inhibition and high cell density deactivate the mammalian target of rapamycin pathway, thus suppressing the senescence program.

Leontieva OV, Demidenko ZN, Blagosklonny MV. Leontieva OV, et al. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8832-7. doi: 10.1073/pnas.1405723111. Epub 2014 Jun 2. Proc Natl Acad Sci U S A. 2014. PMID: 24889617 Free PMC article.

4

Exploring long-term protection of normal human fibroblasts and epithelial cells from chemotherapy in cell culture.

Apontes P, Leontieva OV, Demidenko ZN, Li F, Blagosklonny MV. Apontes P, et al. Among authors: leontieva ov. Oncotarget. 2011 Mar;2(3):222-33. doi: 10.18632/oncotarget.248. Oncotarget. 2011. PMID: 21447859 Free PMC article.

5

S6K in geroconversion.

Leontieva OV, Demidenko ZN, Blagosklonny MV. Leontieva OV, et al. Cell Cycle. 2013 Oct 15;12(20):3249-52. doi: 10.4161/cc.26248. Epub 2013 Sep 9. Cell Cycle. 2013. PMID: 24036549 Free PMC article.

6

Hypoxia suppresses conversion from proliferative arrest to cellular senescence.

Leontieva OV, Natarajan V, Demidenko ZN, Burdelya LG, Gudkov AV, Blagosklonny MV. Leontieva OV, et al. Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13314-8. doi: 10.1073/pnas.1205690109. Epub 2012 Jul 30. Proc Natl Acad Sci U S A. 2012. PMID: 22847439 Free PMC article.

7

Hyper-mitogenic drive coexists with mitotic incompetence in senescent cells.

Leontieva OV, Lenzo F, Demidenko ZN, Blagosklonny MV. Leontieva OV, et al. Cell Cycle. 2012 Dec 15;11(24):4642-9. doi: 10.4161/cc.22937. Epub 2012 Nov 27. Cell Cycle. 2012. PMID: 23187803 Free PMC article.

8

The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway.

Korotchkina LG, Leontieva OV, Bukreeva EI, Demidenko ZN, Gudkov AV, Blagosklonny MV. Korotchkina LG, et al. Among authors: leontieva ov. Aging (Albany NY). 2010 Jun;2(6):344-52. doi: 10.18632/aging.100160. Aging (Albany NY). 2010. PMID: 20606252 Free PMC article.

9

Elimination of proliferating cells unmasks the shift from senescence to quiescence caused by rapamycin.

Leontieva OV, Demidenko ZN, Gudkov AV, Blagosklonny MV. Leontieva OV, et al. PLoS One. 2011;6(10):e26126. doi: 10.1371/journal.pone.0026126. Epub 2011 Oct 11. PLoS One. 2011. PMID: 22022534 Free PMC article.

10

MEK drives cyclin D1 hyperelevation during geroconversion.

Leontieva OV, Demidenko ZN, Blagosklonny MV. Leontieva OV, et al. Cell Death Differ. 2013 Sep;20(9):1241-9. doi: 10.1038/cdd.2013.86. Epub 2013 Jul 12. Cell Death Differ. 2013. PMID: 23852369 Free PMC article.

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