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The Mir181ab1 cluster promotes KRAS-driven oncogenesis and progression in lung and pancreas.
Valencia K, Erice O, Kostyrko K, Hausmann S, Guruceaga E, Tathireddy A, Flores NM, Sayles LC, Lee AG, Fragoso R, Sun TQ, Vallejo A, Roman M, Entrialgo-Cadierno R, Migueliz I, Razquin N, Fortes P, Lecanda F, Lu J, Ponz-Sarvise M, Chen CZ, Mazur PK, Sweet-Cordero EA, Vicent S. Valencia K, et al. Among authors: fragoso r. J Clin Invest. 2020 Apr 1;130(4):1879-1895. doi: 10.1172/JCI129012. J Clin Invest. 2020. PMID: 31874105 Free PMC article.
Phosphatidylinositol 3-kinase inhibition potentiates glucocorticoid response in B-cell acute lymphoblastic leukemia.
Evangelisti C, Cappellini A, Oliveira M, Fragoso R, Barata JT, Bertaina A, Locatelli F, Simioni C, Neri LM, Chiarini F, Lonetti A, Buontempo F, Orsini E, Pession A, Manzoli L, Martelli AM, Evangelisti C. Evangelisti C, et al. Among authors: fragoso r. J Cell Physiol. 2018 Mar;233(3):1796-1811. doi: 10.1002/jcp.26135. Epub 2017 Sep 7. J Cell Physiol. 2018. PMID: 28777460
Interleukin-7 receptor α mutational activation can initiate precursor B-cell acute lymphoblastic leukemia.
Almeida ARM, Neto JL, Cachucho A, Euzébio M, Meng X, Kim R, Fernandes MB, Raposo B, Oliveira ML, Ribeiro D, Fragoso R, Zenatti PP, Soares T, de Matos MR, Corrêa JR, Duque M, Roberts KG, Gu Z, Qu C, Pereira C, Pyne S, Pyne NJ, Barreto VM, Bernard-Pierrot I, Clappier E, Mullighan CG, Grosso AR, Yunes JA, Barata JT. Almeida ARM, et al. Among authors: fragoso r. Nat Commun. 2021 Dec 14;12(1):7268. doi: 10.1038/s41467-021-27197-5. Nat Commun. 2021. PMID: 34907175 Free PMC article.
127 results