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Nonreplicating vaccines can protect african green monkeys from the memphis 37 strain of respiratory syncytial virus.
Eyles JE, Johnson JE, Megati S, Roopchand V, Cockle PJ, Weeratna R, Makinen S, Brown TP, Lang S, Witko SE, Kotash CS, Li J, West K, Maldonado O, Falconer DJ, Lees C, Smith GJ, White P, Wright P, Loudon PT, Merson JR, Jansen KU, Sidhu MK. Eyles JE, et al. Among authors: kotash cs. J Infect Dis. 2013 Jul 15;208(2):319-29. doi: 10.1093/infdis/jit169. Epub 2013 Apr 17. J Infect Dis. 2013. PMID: 23596321
Non-propagating, recombinant vesicular stomatitis virus vectors encoding respiratory syncytial virus proteins generate potent humoral and cellular immunity against RSV and are protective in mice.
Johnson JE, McNeil LK, Megati S, Witko SE, Roopchand VS, Obregon JH, Illenberger DM, Kotash CS, Nowak RM, Braunstein E, Yurgelonis I, Jansen KU, Kalyan NK, Sidhu MK. Johnson JE, et al. Among authors: kotash cs. Immunol Lett. 2013 Feb;150(1-2):134-44. doi: 10.1016/j.imlet.2012.12.005. Epub 2012 Dec 20. Immunol Lett. 2013. PMID: 23261719
A novel approach to generate a recombinant toxoid vaccine against Clostridium difficile.
Donald RGK, Flint M, Kalyan N, Johnson E, Witko SE, Kotash C, Zhao P, Megati S, Yurgelonis I, Lee PK, Matsuka YV, Severina E, Deatly A, Sidhu M, Jansen KU, Minton NP, Anderson AS. Donald RGK, et al. Microbiology (Reading). 2013 Jul;159(Pt 7):1254-1266. doi: 10.1099/mic.0.066712-0. Epub 2013 Apr 29. Microbiology (Reading). 2013. PMID: 23629868 Free PMC article.
Neurovirulence and immunogenicity of attenuated recombinant vesicular stomatitis viruses in nonhuman primates.
Clarke DK, Nasar F, Chong S, Johnson JE, Coleman JW, Lee M, Witko SE, Kotash CS, Abdullah R, Megati S, Luckay A, Nowak B, Lackner A, Price RE, Little P, Kalyan N, Randolf V, Javadian A, Zamb TJ, Parks CL, Egan MA, Eldridge J, Hendry M, Udem SA. Clarke DK, et al. Among authors: kotash cs. J Virol. 2014 Jun;88(12):6690-701. doi: 10.1128/JVI.03441-13. Epub 2014 Apr 2. J Virol. 2014. PMID: 24696472 Free PMC article.
An efficient helper-virus-free method for rescue of recombinant paramyxoviruses and rhadoviruses from a cell line suitable for vaccine development.
Witko SE, Kotash CS, Nowak RM, Johnson JE, Boutilier LA, Melville KJ, Heron SG, Clarke DK, Abramovitz AS, Hendry RM, Sidhu MS, Udem SA, Parks CL. Witko SE, et al. Among authors: kotash cs. J Virol Methods. 2006 Jul;135(1):91-101. doi: 10.1016/j.jviromet.2006.02.006. Epub 2006 Mar 29. J Virol Methods. 2006. PMID: 16569439
Attenuation of recombinant vesicular stomatitis virus-human immunodeficiency virus type 1 vaccine vectors by gene translocations and g gene truncation reduces neurovirulence and enhances immunogenicity in mice.
Cooper D, Wright KJ, Calderon PC, Guo M, Nasar F, Johnson JE, Coleman JW, Lee M, Kotash C, Yurgelonis I, Natuk RJ, Hendry RM, Udem SA, Clarke DK. Cooper D, et al. J Virol. 2008 Jan;82(1):207-19. doi: 10.1128/JVI.01515-07. Epub 2007 Oct 17. J Virol. 2008. PMID: 17942549 Free PMC article.