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Primary melanoma of the CNS in children is driven by congenital expression of oncogenic NRAS in melanocytes.
Pedersen M, Küsters-Vandevelde HVN, Viros A, Groenen PJTA, Sanchez-Laorden B, Gilhuis JH, van Engen-van Grunsven IA, Renier W, Schieving J, Niculescu-Duvaz I, Springer CJ, Küsters B, Wesseling P, Blokx WAM, Marais R. Pedersen M, et al. Among authors: kusters vandevelde hvn, kusters b. Cancer Discov. 2013 Apr;3(4):458-469. doi: 10.1158/2159-8290.CD-12-0464. Epub 2013 Jan 9. Cancer Discov. 2013. PMID: 23303902 Free PMC article.
Experimental treatment of NRAS-mutated neurocutaneous melanocytosis with MEK162, a MEK-inhibitor.
Küsters-Vandevelde HV, Willemsen AE, Groenen PJ, Küsters B, Lammens M, Wesseling P, Djafarihamedani M, Rijntjes J, Delye H, Willemsen MA, van Herpen CM, Blokx WA. Küsters-Vandevelde HV, et al. Among authors: kusters b. Acta Neuropathol Commun. 2014 Apr 8;2:41. doi: 10.1186/2051-5960-2-41. Acta Neuropathol Commun. 2014. PMID: 24713450 Free PMC article.
Adrenal nodularity and somatic mutations in primary aldosteronism: one node is the culprit?
Dekkers T, ter Meer M, Lenders JW, Hermus AR, Schultze Kool L, Langenhuijsen JF, Nishimoto K, Ogishima T, Mukai K, Azizan EA, Tops B, Deinum J, Küsters B. Dekkers T, et al. Among authors: kusters b. J Clin Endocrinol Metab. 2014 Jul;99(7):E1341-51. doi: 10.1210/jc.2013-4255. Epub 2014 Apr 23. J Clin Endocrinol Metab. 2014. PMID: 24758183
Mutations in g protein encoding genes and chromosomal alterations in primary leptomeningeal melanocytic neoplasms.
Küsters-Vandevelde HV, van Engen-van Grunsven IA, Coupland SE, Lake SL, Rijntjes J, Pfundt R, Küsters B, Wesseling P, Blokx WA, Groenen PJ. Küsters-Vandevelde HV, et al. Among authors: kusters b. Pathol Oncol Res. 2015 Apr;21(2):439-47. doi: 10.1007/s12253-014-9841-3. Epub 2014 Oct 15. Pathol Oncol Res. 2015. PMID: 25315378 Free article.
SF3B1 and EIF1AX mutations occur in primary leptomeningeal melanocytic neoplasms; yet another similarity to uveal melanomas.
Küsters-Vandevelde HV, Creytens D, van Engen-van Grunsven AC, Jeunink M, Winnepenninckx V, Groenen PJ, Küsters B, Wesseling P, Blokx WA, Prinsen CF. Küsters-Vandevelde HV, et al. Among authors: kusters b. Acta Neuropathol Commun. 2016 Jan 15;4:5. doi: 10.1186/s40478-016-0272-0. Acta Neuropathol Commun. 2016. PMID: 26769193 Free PMC article.
Copy number variation analysis and methylome profiling of a GNAQ-mutant primary meningeal melanocytic tumor and its liver metastasis.
Küsters-Vandevelde HV, Kruse V, Van Maerken T, Boterberg T, Pfundt R, Creytens D, Van den Broecke C, Machielsen TC, Koelsche C, von Deimling A, Küsters B, Groenen PJ, Wesseling P, Blokx WA. Küsters-Vandevelde HV, et al. Among authors: kusters b. Exp Mol Pathol. 2017 Feb;102(1):25-31. doi: 10.1016/j.yexmp.2016.12.006. Epub 2016 Dec 11. Exp Mol Pathol. 2017. PMID: 27974237
133 results