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Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia.
Roberts EW, Deonarine A, Jones JO, Denton AE, Feig C, Lyons SK, Espeli M, Kraman M, McKenna B, Wells RJ, Zhao Q, Caballero OL, Larder R, Coll AP, O'Rahilly S, Brindle KM, Teichmann SA, Tuveson DA, Fearon DT. Roberts EW, et al. Among authors: lyons sk. J Exp Med. 2013 Jun 3;210(6):1137-51. doi: 10.1084/jem.20122344. Epub 2013 May 27. J Exp Med. 2013. PMID: 23712428 Free PMC article.
Imaging sialylated tumor cell glycans in vivo.
Neves AA, Stöckmann H, Harmston RR, Pryor HJ, Alam IS, Ireland-Zecchini H, Lewis DY, Lyons SK, Leeper FJ, Brindle KM. Neves AA, et al. Among authors: lyons sk. FASEB J. 2011 Aug;25(8):2528-37. doi: 10.1096/fj.10-178590. Epub 2011 Apr 14. FASEB J. 2011. PMID: 21493886
Development of Timd2 as a reporter gene for MRI.
Patrick PS, Rodrigues TB, Kettunen MI, Lyons SK, Neves AA, Brindle KM. Patrick PS, et al. Among authors: lyons sk. Magn Reson Med. 2016 Apr;75(4):1697-707. doi: 10.1002/mrm.25750. Epub 2015 May 15. Magn Reson Med. 2016. PMID: 25981669 Free PMC article.
(13) C magnetic resonance spectroscopy measurements with hyperpolarized [1-(13) C] pyruvate can be used to detect the expression of transgenic pyruvate decarboxylase activity in vivo.
Dzien P, Tee SS, Kettunen MI, Lyons SK, Larkin TJ, Timm KN, Hu DE, Wright A, Rodrigues TB, Serrao EM, Marco-Rius I, Mannion E, D'Santos P, Kennedy BW, Brindle KM. Dzien P, et al. Among authors: lyons sk. Magn Reson Med. 2016 Aug;76(2):391-401. doi: 10.1002/mrm.25879. Epub 2015 Sep 21. Magn Reson Med. 2016. PMID: 26388418 Free PMC article.
The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis.
Massie CE, Lynch A, Ramos-Montoya A, Boren J, Stark R, Fazli L, Warren A, Scott H, Madhu B, Sharma N, Bon H, Zecchini V, Smith DM, Denicola GM, Mathews N, Osborne M, Hadfield J, Macarthur S, Adryan B, Lyons SK, Brindle KM, Griffiths J, Gleave ME, Rennie PS, Neal DE, Mills IG. Massie CE, et al. Among authors: lyons sk. EMBO J. 2011 May 20;30(13):2719-33. doi: 10.1038/emboj.2011.158. EMBO J. 2011. PMID: 21602788 Free PMC article.
Dual-modality gene reporter for in vivo imaging.
Patrick PS, Hammersley J, Loizou L, Kettunen MI, Rodrigues TB, Hu DE, Tee SS, Hesketh R, Lyons SK, Soloviev D, Lewis DY, Aime S, Fulton SM, Brindle KM. Patrick PS, et al. Among authors: lyons sk. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):415-20. doi: 10.1073/pnas.1319000111. Epub 2013 Dec 17. Proc Natl Acad Sci U S A. 2014. PMID: 24347640 Free PMC article.
139 results