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Prophylactic Mitigation of Acute Graft versus Host Disease by Novel 2-(Pyrrolidin-1-ylmethyl)pyrrole-Based Stimulation-2 (ST2) Inhibitors.
Yuan X, Jiang H, Fu D, Rech JC, Robida A, Rajanayake K, Yuan H, He M, Wen B, Sun D, Liu C, Chinnaswamy K, Stuckey JA, Paczesny S, Yang CY. Yuan X, et al. Among authors: robida a. ACS Pharmacol Transl Sci. 2023 Aug 16;6(9):1275-1287. doi: 10.1021/acsptsci.3c00122. eCollection 2023 Sep 8. ACS Pharmacol Transl Sci. 2023. PMID: 37705593
Targeting Lymphoma-associated Macrophage Expansion via CSF1R/JAK Inhibition is a Therapeutic Vulnerability in Peripheral T-cell Lymphomas.
Gao X, Kady N, Wang C, Abdelrahman S, Gann P, Sverdlov M, Wolfe A, Brown N, Reneau J, Robida AM, Murga-Zamalloa C, Wilcox RA. Gao X, et al. Among authors: robida am. Cancer Res Commun. 2022 Dec 30;2(12):1727-1737. doi: 10.1158/2767-9764.CRC-22-0336. eCollection 2022 Dec. Cancer Res Commun. 2022. PMID: 36970721 Free PMC article.
Structure-Activity relationship of 1-(Furan-2ylmethyl)Pyrrolidine-Based Stimulation-2 (ST2) inhibitors for treating graft versus host disease.
Yuan X, Jiang H, Fu D, Robida A, Rajanayake K, Yuan H, Wen B, Sun D, Watch BT, Chinnaswamy K, Stuckey JA, Paczesny S, Rech JC, Yang CY. Yuan X, et al. Among authors: robida a. Bioorg Med Chem. 2022 Oct 1;71:116942. doi: 10.1016/j.bmc.2022.116942. Epub 2022 Jul 22. Bioorg Med Chem. 2022. PMID: 35930851 Free PMC article.
Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1.
Tsou PS, Lu C, Gurrea-Rubio M, Muraoka S, Campbell PL, Wu Q, Model EN, Lind ME, Vichaikul S, Mattichak MN, Brodie WD, Hervoso JL, Ory S, Amarista CI, Pervez R, Junginger L, Ali M, Hodish G, O'Mara MM, Ruth JH, Robida AM, Alt AJ, Zhang C, Urquhart AG, Lawton JN, Chung KC, Maerz T, Saunders TL, Groppi VE, Fox DA, Amin MA. Tsou PS, et al. Among authors: robida am. J Clin Invest. 2022 Jun 1;132(11):e151827. doi: 10.1172/JCI151827. J Clin Invest. 2022. PMID: 35439173 Free PMC article.
From proteomics to discovery of first-in-class ST2 inhibitors active in vivo.
Ramadan AM, Daguindau E, Rech JC, Chinnaswamy K, Zhang J, Hura GL, Griesenauer B, Bolten Z, Robida A, Larsen M, Stuckey JA, Yang CY, Paczesny S. Ramadan AM, et al. Among authors: robida a. JCI Insight. 2018 Jul 26;3(14):e99208. doi: 10.1172/jci.insight.99208. eCollection 2018 Jul 26. JCI Insight. 2018. PMID: 30046004 Free PMC article.
40 results