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The β-arrestin-biased ligand TRV120023 inhibits angiotensin II-induced cardiac hypertrophy while preserving enhanced myofilament response to calcium.
Monasky MM, Taglieri DM, Henze M, Warren CM, Utter MS, Soergel DG, Violin JD, Solaro RJ. Monasky MM, et al. Among authors: henze m. Am J Physiol Heart Circ Physiol. 2013 Sep 15;305(6):H856-66. doi: 10.1152/ajpheart.00327.2013. Epub 2013 Jul 19. Am J Physiol Heart Circ Physiol. 2013. PMID: 23873795 Free PMC article.
A myosin activator improves actin assembly and sarcomere function of human-induced pluripotent stem cell-derived cardiomyocytes with a troponin T point mutation.
Broughton KM, Li J, Sarmah E, Warren CM, Lin YH, Henze MP, Sanchez-Freire V, Solaro RJ, Russell B. Broughton KM, et al. Among authors: henze mp. Am J Physiol Heart Circ Physiol. 2016 Jul 1;311(1):H107-17. doi: 10.1152/ajpheart.00162.2016. Epub 2016 May 6. Am J Physiol Heart Circ Physiol. 2016. PMID: 27199119 Free PMC article.
CRNK gene transfer improves function and reverses the myosin heavy chain isoenzyme switch during post-myocardial infarction left ventricular remodeling.
Hart DL, Heidkamp MC, Iyengar R, Vijayan K, Szotek EL, Barakat JA, Leya M, Henze M, Scrogin K, Henderson KK, Samarel AM. Hart DL, et al. Among authors: henze m. J Mol Cell Cardiol. 2008 Jul;45(1):93-105. doi: 10.1016/j.yjmcc.2008.04.002. Epub 2008 Apr 16. J Mol Cell Cardiol. 2008. PMID: 18495152 Free PMC article.
Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers.
Anderson RL, Trivedi DV, Sarkar SS, Henze M, Ma W, Gong H, Rogers CS, Gorham JM, Wong FL, Morck MM, Seidman JG, Ruppel KM, Irving TC, Cooke R, Green EM, Spudich JA. Anderson RL, et al. Among authors: henze m. Proc Natl Acad Sci U S A. 2018 Aug 28;115(35):E8143-E8152. doi: 10.1073/pnas.1809540115. Epub 2018 Aug 13. Proc Natl Acad Sci U S A. 2018. PMID: 30104387 Free PMC article.
147 results