Samulski RJ - Search Results

1

Comparison of fetal mesencephalic grafts, AAV-delivered GDNF, and both combined in an MPTP-induced nonhuman primate Parkinson's model.

Redmond DE Jr, McEntire CR, Kingsbery JP, Leranth C, Elsworth JD, Bjugstad KB, Roth RH, Samulski RJ, Sladek JR Jr. Redmond DE Jr, et al. Among authors: samulski rj. Mol Ther. 2013 Dec;21(12):2160-8. doi: 10.1038/mt.2013.180. Epub 2013 Aug 5. Mol Ther. 2013. PMID: 23913185 Free PMC article.

2

In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector.

During MJ, Samulski RJ, Elsworth JD, Kaplitt MG, Leone P, Xiao X, Li J, Freese A, Taylor JR, Roth RH, Sladek JR Jr, O'Malley KL, Redmond DE Jr. During MJ, et al. Among authors: samulski rj. Gene Ther. 1998 Jun;5(6):820-7. doi: 10.1038/sj.gt.3300650. Gene Ther. 1998. PMID: 9747462

3

AAV2-mediated gene transfer of GDNF to the striatum of MPTP monkeys enhances the survival and outgrowth of co-implanted fetal dopamine neurons.

Elsworth JD, Redmond DE Jr, Leranth C, Bjugstad KB, Sladek JR Jr, Collier TJ, Foti SB, Samulski RJ, Vives KP, Roth RH. Elsworth JD, et al. Among authors: samulski rj. Exp Neurol. 2008 May;211(1):252-8. doi: 10.1016/j.expneurol.2008.01.026. Epub 2008 Feb 15. Exp Neurol. 2008. PMID: 18346734 Free PMC article.

4

Engineering and selection of shuffled AAV genomes: a new strategy for producing targeted biological nanoparticles.

Li W, Asokan A, Wu Z, Van Dyke T, DiPrimio N, Johnson JS, Govindaswamy L, Agbandje-McKenna M, Leichtle S, Redmond DE Jr, McCown TJ, Petermann KB, Sharpless NE, Samulski RJ. Li W, et al. Among authors: samulski rj. Mol Ther. 2008 Jul;16(7):1252-60. doi: 10.1038/mt.2008.100. Epub 2008 May 20. Mol Ther. 2008. PMID: 18500254 Free PMC article.

5

Embryonic substantia nigra grafts in the mesencephalon send neurites to the host striatum in non-human primate after overexpression of GDNF.

Redmond DE Jr, Elsworth JD, Roth RH, Leranth C, Collier TJ, Blanchard B, Bjugstad KB, Samulski RJ, Aebischer P, Sladek JR Jr. Redmond DE Jr, et al. Among authors: samulski rj. J Comp Neurol. 2009 Jul 1;515(1):31-40. doi: 10.1002/cne.22028. J Comp Neurol. 2009. PMID: 19399891 Free PMC article.

6

Comparative transduction efficiency of AAV vector serotypes 1-6 in the substantia nigra and striatum of the primate brain.

Markakis EA, Vives KP, Bober J, Leichtle S, Leranth C, Beecham J, Elsworth JD, Roth RH, Samulski RJ, Redmond DE Jr. Markakis EA, et al. Among authors: samulski rj. Mol Ther. 2010 Mar;18(3):588-93. doi: 10.1038/mt.2009.286. Epub 2009 Dec 15. Mol Ther. 2010. PMID: 20010918 Free PMC article.

7

Robust spinal motor neuron transduction following intrathecal delivery of AAV9 in pigs.

Federici T, Taub JS, Baum GR, Gray SJ, Grieger JC, Matthews KA, Handy CR, Passini MA, Samulski RJ, Boulis NM. Federici T, et al. Among authors: samulski rj. Gene Ther. 2012 Aug;19(8):852-9. doi: 10.1038/gt.2011.130. Epub 2011 Sep 15. Gene Ther. 2012. PMID: 21918551

8

The AAV vector toolkit: poised at the clinical crossroads.

Asokan A, Schaffer DV, Samulski RJ. Asokan A, et al. Among authors: samulski rj. Mol Ther. 2012 Apr;20(4):699-708. doi: 10.1038/mt.2011.287. Epub 2012 Jan 24. Mol Ther. 2012. PMID: 22273577 Free PMC article. Review.

9

Human neural stem cells survive long term in the midbrain of dopamine-depleted monkeys after GDNF overexpression and project neurites toward an appropriate target.

Wakeman DR, Redmond DE Jr, Dodiya HB, Sladek JR Jr, Leranth C, Teng YD, Samulski RJ, Snyder EY. Wakeman DR, et al. Among authors: samulski rj. Stem Cells Transl Med. 2014 Jun;3(6):692-701. doi: 10.5966/sctm.2013-0208. Epub 2014 Apr 17. Stem Cells Transl Med. 2014. PMID: 24744393 Free PMC article.

10

AAVR: A Multi-Serotype Receptor for AAV.

Summerford C, Johnson JS, Samulski RJ. Summerford C, et al. Among authors: samulski rj. Mol Ther. 2016 Apr;24(4):663-6. doi: 10.1038/mt.2016.49. Mol Ther. 2016. PMID: 27081719 Free PMC article. No abstract available.

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