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MEK5/ERK5 signaling suppresses estrogen receptor expression and promotes hormone-independent tumorigenesis.
Antoon JW, Martin EC, Lai R, Salvo VA, Tang Y, Nitzchke AM, Elliott S, Nam SY, Xiong W, Rhodes LV, Collins-Burow B, David O, Wang G, Shan B, Beckman BS, Nephew KP, Burow ME. Antoon JW, et al. Among authors: beckman bs. PLoS One. 2013 Aug 9;8(8):e69291. doi: 10.1371/journal.pone.0069291. eCollection 2013. PLoS One. 2013. PMID: 23950888 Free PMC article.
Proteomic analysis of tumor necrosis factor-alpha resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype.
Zhou C, Nitschke AM, Xiong W, Zhang Q, Tang Y, Bloch M, Elliott S, Zhu Y, Bazzone L, Yu D, Weldon CB, Schiff R, McLachlan JA, Beckman BS, Wiese TE, Nephew KP, Shan B, Burow ME, Wang G. Zhou C, et al. Among authors: beckman bs. Breast Cancer Res. 2008;10(6):R105. doi: 10.1186/bcr2210. Epub 2008 Dec 16. Breast Cancer Res. 2008. PMID: 19087274 Free PMC article.
Adult human mesenchymal stem cells enhance breast tumorigenesis and promote hormone independence.
Rhodes LV, Muir SE, Elliott S, Guillot LM, Antoon JW, Penfornis P, Tilghman SL, Salvo VA, Fonseca JP, Lacey MR, Beckman BS, McLachlan JA, Rowan BG, Pochampally R, Burow ME. Rhodes LV, et al. Among authors: beckman bs. Breast Cancer Res Treat. 2010 Jun;121(2):293-300. doi: 10.1007/s10549-009-0458-2. Epub 2009 Jul 12. Breast Cancer Res Treat. 2010. PMID: 19597705 Free PMC article.
Cytokine receptor CXCR4 mediates estrogen-independent tumorigenesis, metastasis, and resistance to endocrine therapy in human breast cancer.
Rhodes LV, Short SP, Neel NF, Salvo VA, Zhu Y, Elliott S, Wei Y, Yu D, Sun M, Muir SE, Fonseca JP, Bratton MR, Segar C, Tilghman SL, Sobolik-Delmaire T, Horton LW, Zaja-Milatovic S, Collins-Burow BM, Wadsworth S, Beckman BS, Wood CE, Fuqua SA, Nephew KP, Dent P, Worthylake RA, Curiel TJ, Hung MC, Richmond A, Burow ME. Rhodes LV, et al. Among authors: beckman bs. Cancer Res. 2011 Jan 15;71(2):603-13. doi: 10.1158/0008-5472.CAN-10-3185. Epub 2010 Dec 1. Cancer Res. 2011. PMID: 21123450 Free PMC article.
MEK5/ERK5 pathway: the first fifteen years.
Drew BA, Burow ME, Beckman BS. Drew BA, et al. Among authors: beckman bs. Biochim Biophys Acta. 2012 Jan;1825(1):37-48. doi: 10.1016/j.bbcan.2011.10.002. Epub 2011 Oct 13. Biochim Biophys Acta. 2012. PMID: 22020294 Free PMC article. Review.
Gαo potentiates estrogen receptor α activity via the ERK signaling pathway.
Bratton MR, Antoon JW, Duong BN, Frigo DE, Tilghman S, Collins-Burow BM, Elliott S, Tang Y, Melnik LI, Lai L, Alam J, Beckman BS, Hill SM, Rowan BG, McLachlan JA, Burow ME. Bratton MR, et al. Among authors: beckman bs. J Endocrinol. 2012 Jul;214(1):45-54. doi: 10.1530/JOE-12-0097. Epub 2012 May 4. J Endocrinol. 2012. PMID: 22562654 Free PMC article.
Antiestrogenic activity of flavonoid phytochemicals mediated via the c-Jun N-terminal protein kinase pathway. Cell-type specific regulation of estrogen receptor alpha.
Collins-Burow BM, Antoon JW, Frigo DE, Elliott S, Weldon CB, Boue SM, Beckman BS, Curiel TJ, Alam J, McLachlan JA, Burow ME. Collins-Burow BM, et al. Among authors: beckman bs. J Steroid Biochem Mol Biol. 2012 Oct;132(1-2):186-93. doi: 10.1016/j.jsbmb.2012.05.004. Epub 2012 May 24. J Steroid Biochem Mol Biol. 2012. PMID: 22634477 Free PMC article.
135 results