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A community challenge for a pancancer drug mechanism of action inference from perturbational profile data.
Douglass EF Jr, Allaway RJ, Szalai B, Wang W, Tian T, Fernández-Torras A, Realubit R, Karan C, Zheng S, Pessia A, Tanoli Z, Jafari M, Wan F, Li S, Xiong Y, Duran-Frigola M, Bertoni M, Badia-I-Mompel P, Mateo L, Guitart-Pla O, Chung V; DREAM CTD-squared Pancancer Drug Activity Challenge Consortium; Tang J, Zeng J, Aloy P, Saez-Rodriguez J, Guinney J, Gerhard DS, Califano A. Douglass EF Jr, et al. Cell Rep Med. 2022 Jan 18;3(1):100492. doi: 10.1016/j.xcrm.2021.100492. eCollection 2022 Jan 18. Cell Rep Med. 2022. PMID: 35106508 Free PMC article.
Identification of natural RORγ ligands that regulate the development of lymphoid cells.
Santori FR, Huang P, van de Pavert SA, Douglass EF Jr, Leaver DJ, Haubrich BA, Keber R, Lorbek G, Konijn T, Rosales BN, Rozman D, Horvat S, Rahier A, Mebius RE, Rastinejad F, Nes WD, Littman DR. Santori FR, et al. Among authors: douglass ef jr. Cell Metab. 2015 Feb 3;21(2):286-298. doi: 10.1016/j.cmet.2015.01.004. Cell Metab. 2015. PMID: 25651181 Free PMC article.
A "turn-on" fluorescent sensor for methylglyoxal.
Wang T, Douglass EF Jr, Fitzgerald KJ, Spiegel DA. Wang T, et al. Among authors: douglass ef jr. J Am Chem Soc. 2013 Aug 21;135(33):12429-33. doi: 10.1021/ja406077j. Epub 2013 Aug 9. J Am Chem Soc. 2013. PMID: 23931147
12 results