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Structure and dynamics of a molten globular enzyme.
Pervushin K, Vamvaca K, Vögeli B, Hilvert D. Pervushin K, et al. Among authors: hilvert d. Nat Struct Mol Biol. 2007 Dec;14(12):1202-6. doi: 10.1038/nsmb1325. Epub 2007 Nov 11. Nat Struct Mol Biol. 2007. PMID: 17994104
Tailor-made peptide synthetases.
Kries H, Hilvert D. Kries H, et al. Among authors: hilvert d. Chem Biol. 2011 Oct 28;18(10):1206-7. doi: 10.1016/j.chembiol.2011.10.006. Chem Biol. 2011. PMID: 22035787
Iterative approach to computational enzyme design.
Privett HK, Kiss G, Lee TM, Blomberg R, Chica RA, Thomas LM, Hilvert D, Houk KN, Mayo SL. Privett HK, et al. Among authors: hilvert d. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3790-5. doi: 10.1073/pnas.1118082108. Epub 2012 Feb 22. Proc Natl Acad Sci U S A. 2012. PMID: 22357762 Free PMC article.
Computational design of catalytic dyads and oxyanion holes for ester hydrolysis.
Richter F, Blomberg R, Khare SD, Kiss G, Kuzin AP, Smith AJ, Gallaher J, Pianowski Z, Helgeson RC, Grjasnow A, Xiao R, Seetharaman J, Su M, Vorobiev S, Lew S, Forouhar F, Kornhaber GJ, Hunt JF, Montelione GT, Tong L, Houk KN, Hilvert D, Baker D. Richter F, et al. Among authors: hilvert d. J Am Chem Soc. 2012 Oct 3;134(39):16197-206. doi: 10.1021/ja3037367. Epub 2012 Sep 21. J Am Chem Soc. 2012. PMID: 22871159 Free PMC article.
De novo enzymes by computational design.
Kries H, Blomberg R, Hilvert D. Kries H, et al. Among authors: hilvert d. Curr Opin Chem Biol. 2013 Apr;17(2):221-8. doi: 10.1016/j.cbpa.2013.02.012. Epub 2013 Mar 14. Curr Opin Chem Biol. 2013. PMID: 23498973 Review.
245 results