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Rule-based models of the interplay between genetic and environmental factors in childhood allergy.
Bornelöv S, Sääf A, Melén E, Bergström A, Torabi Moghadam B, Pulkkinen V, Acevedo N, Orsmark Pietras C, Ege M, Braun-Fahrländer C, Riedler J, Doekes G, Kabesch M, van Hage M, Kere J, Scheynius A, Söderhäll C, Pershagen G, Komorowski J. Bornelöv S, et al. Among authors: doekes g. PLoS One. 2013 Nov 19;8(11):e80080. doi: 10.1371/journal.pone.0080080. eCollection 2013. PLoS One. 2013. PMID: 24260339 Free PMC article.
Interaction between retinoid acid receptor-related orphan receptor alpha (RORA) and neuropeptide S receptor 1 (NPSR1) in asthma.
Acevedo N, Sääf A, Söderhäll C, Melén E, Mandelin J, Pietras CO, Ezer S, Karisola P, Vendelin J, Gennäs GB, Yli-Kauhaluoma J, Alenius H, von Mutius E, Doekes G, Braun-Fahrländer C, Riedler J, van Hage M, D'Amato M, Scheynius A, Pershagen G, Kere J, Pulkkinen V. Acevedo N, et al. Among authors: doekes g. PLoS One. 2013;8(4):e60111. doi: 10.1371/journal.pone.0060111. Epub 2013 Apr 2. PLoS One. 2013. PMID: 23565190 Free PMC article.
Haplotypes of G protein-coupled receptor 154 are associated with childhood allergy and asthma.
Melén E, Bruce S, Doekes G, Kabesch M, Laitinen T, Lauener R, Lindgren CM, Riedler J, Scheynius A, van Hage-Hamsten M, Kere J, Pershagen G, Wickman M, Nyberg F; PARSIFAL Genetics Study Group. Melén E, et al. Among authors: doekes g. Am J Respir Crit Care Med. 2005 May 15;171(10):1089-95. doi: 10.1164/rccm.200410-1317OC. Epub 2005 Feb 11. Am J Respir Crit Care Med. 2005. PMID: 15710598
Biological and genetic interaction between tenascin C and neuropeptide S receptor 1 in allergic diseases.
Orsmark-Pietras C, Melén E, Vendelin J, Bruce S, Laitinen A, Laitinen LA, Lauener R, Riedler J, von Mutius E, Doekes G, Wickman M, van Hage M, Pershagen G, Scheynius A, Nyberg F, Kere J; PARSIFAL Genetics Study Group. Orsmark-Pietras C, et al. Among authors: doekes g. Hum Mol Genet. 2008 Jun 1;17(11):1673-82. doi: 10.1093/hmg/ddn058. Epub 2008 Feb 27. Hum Mol Genet. 2008. PMID: 18305139 Free article.
Lack of association between neuropeptide S receptor 1 gene (NPSR1) and eczema in five European populations.
Ekelund E, Bradley M, Weidinger S, Jovanovic DL, Johansson C, Lindgren CM, Todorova A, Jakob T, Illig T, von Mutius E, Braun-Fahrländer C, Doekes G, Riedler J, Scheynius A, Pershagen G, Kockum I, Kere J. Ekelund E, et al. Among authors: doekes g. Acta Derm Venereol. 2009;89(2):115-21. doi: 10.2340/00015555-0549. Acta Derm Venereol. 2009. PMID: 19325992 Free article.
The protective effect of farm animal exposure on childhood allergy is modified by NPSR1 polymorphisms.
Bruce S, Nyberg F, Melén E, James A, Pulkkinen V, Orsmark-Pietras C, Bergström A, Dahlén B, Wickman M, von Mutius E, Doekes G, Lauener R, Riedler J, Eder W, van Hage M, Pershagen G, Scheynius A, Kere J. Bruce S, et al. Among authors: doekes g. J Med Genet. 2009 Mar;46(3):159-67. doi: 10.1136/jmg.2007.055137. Epub 2008 Feb 19. J Med Genet. 2009. PMID: 18285428 Free article.
Expression of genes related to anti-inflammatory pathways are modified among farmers' children.
Frei R, Roduit C, Bieli C, Loeliger S, Waser M, Scheynius A, van Hage M, Pershagen G, Doekes G, Riedler J, von Mutius E, Sennhauser F, Akdis CA, Braun-Fahrländer C, Lauener RP; as part of the PARSIFAL study team. Frei R, et al. Among authors: doekes g. PLoS One. 2014 Mar 6;9(3):e91097. doi: 10.1371/journal.pone.0091097. eCollection 2014. PLoS One. 2014. PMID: 24603716 Free PMC article.
A comprehensive analysis of the COL29A1 gene does not support a role in eczema.
Naumann A, Söderhäll C, Fölster-Holst R, Baurecht H, Harde V, Müller-Wehling K, Rodríguez E, Ruether A, Franke A, Wagenpfeil S, Novak N, Mempel M, Kalali BN, Allgaeuer M, Koch J, Gerhard M, Melén E, Wahlgren CF, Kull I, Stahl C, Pershagen G, Lauener R, Riedler J, Doekes G, Scheynius A, Illig T, von Mutius E, Schreiber S, Kere J, Kabesch M, Weidinger S. Naumann A, et al. Among authors: doekes g. J Allergy Clin Immunol. 2011 May;127(5):1187-94.e7. doi: 10.1016/j.jaci.2010.12.1123. Epub 2011 Feb 25. J Allergy Clin Immunol. 2011. PMID: 21353297
Exposure to nonmicrobial N-glycolylneuraminic acid protects farmers' children against airway inflammation and colitis.
Frei R, Ferstl R, Roduit C, Ziegler M, Schiavi E, Barcik W, Rodriguez-Perez N, Wirz OF, Wawrzyniak M, Pugin B, Nehrbass D, Jutel M, Smolinska S, Konieczna P, Bieli C, Loeliger S, Waser M, Pershagen G, Riedler J, Depner M, Schaub B, Genuneit J, Renz H, Pekkanen J, Karvonen AM, Dalphin JC, van Hage M, Doekes G, Akdis M, Braun-Fahrländer C, Akdis CA, von Mutius E, O'Mahony L, Lauener RP; Prevention of Allergy Risk factors for Sensitization in Children Related to Farming and Anthroposophic Lifestyle (PARSIFAL) study group; Protection Against Allergy Study in Rural Environments (PASTURE)/Mechanisms of Early Protective Exposures on Allergy Development (EFRAIM) study group. Frei R, et al. Among authors: doekes g. J Allergy Clin Immunol. 2018 Jan;141(1):382-390.e7. doi: 10.1016/j.jaci.2017.04.051. Epub 2017 Jun 17. J Allergy Clin Immunol. 2018. PMID: 28629745 Free article.
A polymorphism in CD14 modifies the effect of farm milk consumption on allergic diseases and CD14 gene expression.
Bieli C, Eder W, Frei R, Braun-Fahrländer C, Klimecki W, Waser M, Riedler J, von Mutius E, Scheynius A, Pershagen G, Doekes G, Lauener R, Martinez FD; PARSIFAL study group. Bieli C, et al. Among authors: doekes g. J Allergy Clin Immunol. 2007 Dec;120(6):1308-15. doi: 10.1016/j.jaci.2007.07.034. Epub 2007 Oct 24. J Allergy Clin Immunol. 2007. PMID: 17919709
191 results