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Androgens and estrogens in skeletal sexual dimorphism.
Laurent M, Antonio L, Sinnesael M, Dubois V, Gielen E, Classens F, Vanderschueren D. Laurent M, et al. Among authors: dubois v. Asian J Androl. 2014 Mar-Apr;16(2):213-22. doi: 10.4103/1008-682X.122356. Asian J Androl. 2014. PMID: 24385015 Free PMC article. Review.
The transcription intermediary factor 1β coactivates the androgen receptor.
Van Tilborgh N, Spans L, Helsen C, Clinckemalie L, Dubois V, Lerut E, Boonen S, Vanderschueren D, Claessens F. Van Tilborgh N, et al. Among authors: dubois v. J Endocrinol Invest. 2013 Oct;36(9):699-706. doi: 10.3275/8927. Epub 2013 Apr 8. J Endocrinol Invest. 2013. PMID: 23563173
A satellite cell-specific knockout of the androgen receptor reveals myostatin as a direct androgen target in skeletal muscle.
Dubois V, Laurent MR, Sinnesael M, Cielen N, Helsen C, Clinckemalie L, Spans L, Gayan-Ramirez G, Deldicque L, Hespel P, Carmeliet G, Vanderschueren D, Claessens F. Dubois V, et al. FASEB J. 2014 Jul;28(7):2979-94. doi: 10.1096/fj.14-249748. Epub 2014 Mar 26. FASEB J. 2014. PMID: 24671706
Our finding that androgens induce Mstn signaling to restrain their own anabolic actions has implications for the treatment of muscle wasting disorders.-Dubois, V., Laurent, M. R., Sinnesael, M., Cielen, N., Helsen, C., Clinckemalie, L., Spans, L., Gayan-Ramirez, G., …
Our finding that androgens induce Mstn signaling to restrain their own anabolic actions has implications for the treatment of muscle wasting …
Androgens inhibit the osteogenic response to mechanical loading in adult male mice.
Sinnesael M, Laurent MR, Jardi F, Dubois V, Deboel L, Delisser P, Behets GJ, D'Haese PC, Carmeliet G, Claessens F, Vanderschueren D. Sinnesael M, et al. Among authors: dubois v. Endocrinology. 2015 Apr;156(4):1343-53. doi: 10.1210/en.2014-1673. Epub 2015 Feb 5. Endocrinology. 2015. PMID: 25654322
The androgen receptor has no direct antiresorptive actions in mouse osteoclasts.
Sinnesael M, Jardi F, Deboel L, Laurent MR, Dubois V, Zajac JD, Davey RA, Carmeliet G, Claessens F, Vanderschueren D. Sinnesael M, et al. Among authors: dubois v. Mol Cell Endocrinol. 2015 Aug 15;411:198-206. doi: 10.1016/j.mce.2015.04.030. Epub 2015 May 6. Mol Cell Endocrinol. 2015. PMID: 25958043
412 results