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Polycomb eviction as a new distant enhancer function.
Vernimmen D, Lynch MD, De Gobbi M, Garrick D, Sharpe JA, Sloane-Stanley JA, Smith AJ, Higgs DR. Vernimmen D, et al. Among authors: lynch md. Genes Dev. 2011 Aug 1;25(15):1583-8. doi: 10.1101/gad.16985411. Genes Dev. 2011. PMID: 21828268 Free PMC article.
Intragenic enhancers act as alternative promoters.
Kowalczyk MS, Hughes JR, Garrick D, Lynch MD, Sharpe JA, Sloane-Stanley JA, McGowan SJ, De Gobbi M, Hosseini M, Vernimmen D, Brown JM, Gray NE, Collavin L, Gibbons RJ, Flint J, Taylor S, Buckle VJ, Milne TA, Wood WG, Higgs DR. Kowalczyk MS, et al. Among authors: lynch md. Mol Cell. 2012 Feb 24;45(4):447-58. doi: 10.1016/j.molcel.2011.12.021. Epub 2012 Jan 19. Mol Cell. 2012. PMID: 22264824 Free article.
Switching genes on and off in haemopoiesis.
Garrick D, De Gobbi M, Lynch M, Higgs DR. Garrick D, et al. Among authors: lynch m. Biochem Soc Trans. 2008 Aug;36(Pt 4):613-8. doi: 10.1042/BST0360613. Biochem Soc Trans. 2008. PMID: 18631127
DNA methylation of intragenic CpG islands depends on their transcriptional activity during differentiation and disease.
Jeziorska DM, Murray RJS, De Gobbi M, Gaentzsch R, Garrick D, Ayyub H, Chen T, Li E, Telenius J, Lynch M, Graham B, Smith AJH, Lund JN, Hughes JR, Higgs DR, Tufarelli C. Jeziorska DM, et al. Among authors: lynch m. Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):E7526-E7535. doi: 10.1073/pnas.1703087114. Epub 2017 Aug 21. Proc Natl Acad Sci U S A. 2017. PMID: 28827334 Free PMC article.
Generation of bivalent chromatin domains during cell fate decisions.
De Gobbi M, Garrick D, Lynch M, Vernimmen D, Hughes JR, Goardon N, Luc S, Lower KM, Sloane-Stanley JA, Pina C, Soneji S, Renella R, Enver T, Taylor S, Jacobsen SE, Vyas P, Gibbons RJ, Higgs DR. De Gobbi M, et al. Among authors: lynch m. Epigenetics Chromatin. 2011 Jun 6;4(1):9. doi: 10.1186/1756-8935-4-9. Epigenetics Chromatin. 2011. PMID: 21645363 Free PMC article.
2,622 results