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Sorafenib dose escalation is not uniformly associated with blood pressure elevations in normotensive patients with advanced malignancies.
Clin Pharmacol Ther. 2014 Jul;96(1):27-35. doi: 10.1038/clpt.2014.63. Epub 2014 Mar 17.
Clin Pharmacol Ther. 2014.
PMID: 24637941
Free PMC article.
Clinical Trial.
Technical considerations in the development of circulating peptides as pharmacodynamic biomarkers for angiogenesis inhibitors.
Thomeas V, Chow S, Gutierrez JO, Karovic S, Wroblewski K, Kistner-Griffin E, Karrison TG, Maitland ML.
Thomeas V, et al.
J Clin Pharmacol. 2014 Jun;54(6):682-7. doi: 10.1002/jcph.254. Epub 2014 Jan 17.
J Clin Pharmacol. 2014.
PMID: 24374901
Free PMC article.
Clinical Trial.
Item in Clipboard
Identification of a variant in KDR associated with serum VEGFR2 and pharmacodynamics of Pazopanib.
Maitland ML, Xu CF, Cheng YC, Kistner-Griffin E, Ryan KA, Karrison TG, Das S, Torgerson D, Gamazon ER, Thomeas V, Levine MR, Wilson PA, Bing N, Liu Y, Cardon LR, Pandite LN, O'Connell JR, Cox NJ, Mitchell BD, Ratain MJ, Shuldiner AR.
Maitland ML, et al. Among authors: thomeas v.
Clin Cancer Res. 2015 Jan 15;21(2):365-72. doi: 10.1158/1078-0432.CCR-14-1683. Epub 2014 Nov 19.
Clin Cancer Res. 2015.
PMID: 25411163
Free PMC article.
Item in Clipboard
Phase I safety study of ranolazine in pulmonary arterial hypertension.
Gomberg-Maitland M, Schilz R, Mediratta A, Addetia K, Coslet S, Thomeas V, Gillies H, Oudiz RJ.
Gomberg-Maitland M, et al. Among authors: thomeas v.
Pulm Circ. 2015 Dec;5(4):691-700. doi: 10.1086/683813.
Pulm Circ. 2015.
PMID: 26697176
Free PMC article.
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Tricuspid regurgitation progression and regression in pulmonary arterial hypertension: implications for right ventricular and tricuspid valve apparatus geometry and patients outcome.
Medvedofsky D, Aronson D, Gomberg-Maitland M, Thomeas V, Rich S, Spencer K, Mor-Avi V, Addetia K, Lang RM, Shiran A.
Medvedofsky D, et al. Among authors: thomeas v.
Eur Heart J Cardiovasc Imaging. 2017 Jan;18(1):86-94. doi: 10.1093/ehjci/jew010. Epub 2016 Feb 11.
Eur Heart J Cardiovasc Imaging. 2017.
PMID: 26873457
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