Morgan RK - Search Results

1

Engineering the substrate specificity of ADP-ribosyltransferases for identifying direct protein targets.

Carter-O'Connell I, Jin H, Morgan RK, David LL, Cohen MS. Carter-O'Connell I, et al. Among authors: morgan rk. J Am Chem Soc. 2014 Apr 9;136(14):5201-4. doi: 10.1021/ja412897a. Epub 2014 Mar 26. J Am Chem Soc. 2014. PMID: 24641686 Free PMC article.

2

A Clickable Aminooxy Probe for Monitoring Cellular ADP-Ribosylation.

Morgan RK, Cohen MS. Morgan RK, et al. ACS Chem Biol. 2015 Aug 21;10(8):1778-84. doi: 10.1021/acschembio.5b00213. Epub 2015 May 27. ACS Chem Biol. 2015. PMID: 25978521 Free PMC article.

3

Selective inhibition of PARP10 using a chemical genetics strategy.

Morgan RK, Carter-O'Connell I, Cohen MS. Morgan RK, et al. Bioorg Med Chem Lett. 2015 Nov 1;25(21):4770-4773. doi: 10.1016/j.bmcl.2015.07.033. Epub 2015 Jul 17. Bioorg Med Chem Lett. 2015. PMID: 26231158 Free PMC article.

4

Identifying Family-Member-Specific Targets of Mono-ARTDs by Using a Chemical Genetics Approach.

Carter-O'Connell I, Jin H, Morgan RK, Zaja R, David LL, Ahel I, Cohen MS. Carter-O'Connell I, et al. Among authors: morgan rk. Cell Rep. 2016 Jan 26;14(3):621-631. doi: 10.1016/j.celrep.2015.12.045. Epub 2016 Jan 7. Cell Rep. 2016. PMID: 26774478 Free PMC article.

5

Biosensor reveals multiple sources for mitochondrial NAD⁺.

Cambronne XA, Stewart ML, Kim D, Jones-Brunette AM, Morgan RK, Farrens DL, Cohen MS, Goodman RH. Cambronne XA, et al. Among authors: morgan rk. Science. 2016 Jun 17;352(6292):1474-7. doi: 10.1126/science.aad5168. Science. 2016. PMID: 27313049 Free PMC article.

6

Detecting Protein ADP-Ribosylation Using a Clickable Aminooxy Probe.

Morgan RK, Cohen MS. Morgan RK, et al. Methods Mol Biol. 2017;1608:71-77. doi: 10.1007/978-1-4939-6993-7_6. Methods Mol Biol. 2017. PMID: 28695504 Free PMC article.

7

A Simple, Sensitive, and Generalizable Plate Assay for Screening PARP Inhibitors.

Kirby IT, Morgan RK, Cohen MS. Kirby IT, et al. Among authors: morgan rk. Methods Mol Biol. 2018;1813:245-252. doi: 10.1007/978-1-4939-8588-3_17. Methods Mol Biol. 2018. PMID: 30097873

8

Combining Chemical Genetics with Proximity-Dependent Labeling Reveals Cellular Targets of Poly(ADP-ribose) Polymerase 14 (PARP14).

Carter-O'Connell I, Vermehren-Schmaedick A, Jin H, Morgan RK, David LL, Cohen MS. Carter-O'Connell I, et al. Among authors: morgan rk. ACS Chem Biol. 2018 Oct 19;13(10):2841-2848. doi: 10.1021/acschembio.8b00567. Epub 2018 Sep 28. ACS Chem Biol. 2018. PMID: 30247868

9

Rational Design of Cell-Active Inhibitors of PARP10.

Morgan RK, Kirby IT, Vermehren-Schmaedick A, Rodriguez K, Cohen MS. Morgan RK, et al. ACS Med Chem Lett. 2018 Nov 29;10(1):74-79. doi: 10.1021/acsmedchemlett.8b00429. eCollection 2019 Jan 10. ACS Med Chem Lett. 2018. PMID: 30655950 Free PMC article.

10

Structure-guided design and characterization of a clickable, covalent PARP16 inhibitor.

Bejan DS, Sundalam S, Jin H, Morgan RK, Kirby IT, Siordia IR, Tivon B, London N, Cohen MS. Bejan DS, et al. Among authors: morgan rk. Chem Sci. 2022 Nov 16;13(46):13898-13906. doi: 10.1039/d2sc04820e. eCollection 2022 Nov 30. Chem Sci. 2022. PMID: 36544740 Free PMC article.

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