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Loss of PINK1 increases the heart's vulnerability to ischemia-reperfusion injury.
Siddall HK, Yellon DM, Ong SB, Mukherjee UA, Burke N, Hall AR, Angelova PR, Ludtmann MH, Deas E, Davidson SM, Mocanu MM, Hausenloy DJ. Siddall HK, et al. Among authors: burke n. PLoS One. 2013 Apr 29;8(4):e62400. doi: 10.1371/journal.pone.0062400. Print 2013. PLoS One. 2013. PMID: 23638067 Free PMC article.
OPA1 in Cardiovascular Health and Disease.
Burke N, Hall AR, Hausenloy DJ. Burke N, et al. Curr Drug Targets. 2015;16(8):912-20. doi: 10.2174/1389450116666150102113648. Curr Drug Targets. 2015. PMID: 25557256 Review.
Losmapimod, a novel p38 mitogen-activated protein kinase inhibitor, in non-ST-segment elevation myocardial infarction: a randomised phase 2 trial.
Newby LK, Marber MS, Melloni C, Sarov-Blat L, Aberle LH, Aylward PE, Cai G, de Winter RJ, Hamm CW, Heitner JF, Kim R, Lerman A, Patel MR, Tanguay JF, Lepore JJ, Al-Khalidi HR, Sprecher DL, Granger CB; SOLSTICE Investigators. Newby LK, et al. Lancet. 2014 Sep 27;384(9949):1187-95. doi: 10.1016/S0140-6736(14)60417-7. Epub 2014 Jun 12. Lancet. 2014. PMID: 24930728 Clinical Trial.
423 results