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ABC transporters in CSCs membranes as a novel target for treating tumor relapse.
Front Pharmacol. 2014 Jul 10;5:163. doi: 10.3389/fphar.2014.00163. eCollection 2014.
Front Pharmacol. 2014.
PMID: 25071581
Free PMC article.
Review.
Small and Innovative Molecules as New Strategy to Revert MDR.
Zinzi L, Capparelli E, Cantore M, Contino M, Leopoldo M, Colabufo NA.
Zinzi L, et al.
Front Oncol. 2014 Jan 21;4:2. doi: 10.3389/fonc.2014.00002. eCollection 2014.
Front Oncol. 2014.
PMID: 24478983
Free PMC article.
Review.
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SAR studies on tetrahydroisoquinoline derivatives: the role of flexibility and bioisosterism to raise potency and selectivity toward P-glycoprotein.
Capparelli E, Zinzi L, Cantore M, Contino M, Perrone MG, Luurtsema G, Berardi F, Perrone R, Colabufo NA.
Capparelli E, et al. Among authors: zinzi l.
J Med Chem. 2014 Dec 11;57(23):9983-94. doi: 10.1021/jm501640e. Epub 2014 Nov 20.
J Med Chem. 2014.
PMID: 25379609
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Potent and selective tariquidar bioisosters as potential PET radiotracers for imaging P-gp.
Contino M, Zinzi L, Perrone MG, Leopoldo M, Berardi F, Perrone R, Colabufo NA.
Contino M, et al. Among authors: zinzi l.
Bioorg Med Chem Lett. 2013 Mar 1;23(5):1370-4. doi: 10.1016/j.bmcl.2012.12.084. Epub 2013 Jan 5.
Bioorg Med Chem Lett. 2013.
PMID: 23374872
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Activity-lipophilicity relationship studies on P-gp ligands designed as simplified tariquidar bulky fragments.
Contino M, Zinzi L, Cantore M, Perrone MG, Leopoldo M, Berardi F, Perrone R, Colabufo NA.
Contino M, et al. Among authors: zinzi l.
Bioorg Med Chem Lett. 2013 Jul 1;23(13):3728-31. doi: 10.1016/j.bmcl.2013.05.019. Epub 2013 May 16.
Bioorg Med Chem Lett. 2013.
PMID: 23726026
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