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The history and market impact of CRISPR RNA-guided nucleases.
van Erp PB, Bloomer G, Wilkinson R, Wiedenheft B. van Erp PB, et al. Curr Opin Virol. 2015 Jun;12:85-90. doi: 10.1016/j.coviro.2015.03.011. Epub 2015 Apr 26. Curr Opin Virol. 2015. PMID: 25914022 Free PMC article.
Conformational regulation of CRISPR-associated nucleases.
Jackson RN, van Erp PB, Sternberg SH, Wiedenheft B. Jackson RN, et al. Among authors: van erp pb. Curr Opin Microbiol. 2017 Jun;37:110-119. doi: 10.1016/j.mib.2017.05.010. Epub 2017 Jun 21. Curr Opin Microbiol. 2017. PMID: 28646675 Free PMC article. Review.
CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3.
Westra ER, van Erp PB, Künne T, Wong SP, Staals RH, Seegers CL, Bollen S, Jore MM, Semenova E, Severinov K, de Vos WM, Dame RT, de Vries R, Brouns SJ, van der Oost J. Westra ER, et al. Among authors: van erp pb. Mol Cell. 2012 Jun 8;46(5):595-605. doi: 10.1016/j.molcel.2012.03.018. Epub 2012 Apr 19. Mol Cell. 2012. PMID: 22521689 Free PMC article.
Cascade-mediated binding and bending of negatively supercoiled DNA.
Westra ER, Nilges B, van Erp PB, van der Oost J, Dame RT, Brouns SJ. Westra ER, et al. Among authors: van erp pb. RNA Biol. 2012 Sep;9(9):1134-8. doi: 10.4161/rna.21410. Epub 2012 Sep 1. RNA Biol. 2012. PMID: 22954644 Free PMC article. Review.