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TDP1 and PARP1 deficiency are cytotoxic to rhabdomyosarcoma cells.
Fam HK, Walton C, Mitra SA, Chowdhury M, Osborne N, Choi K, Sun G, Wong PC, O'Sullivan MJ, Turashvili G, Aparicio S, Triche TJ, Bond M, Pallen CJ, Boerkoel CF. Fam HK, et al. Mol Cancer Res. 2013 Oct;11(10):1179-92. doi: 10.1158/1541-7786.MCR-12-0575. Epub 2013 Aug 2. Mol Cancer Res. 2013. PMID: 23913164
Penetrance of biallelic SMARCAL1 mutations is associated with environmental and genetic disturbances of gene expression.
Baradaran-Heravi A, Cho KS, Tolhuis B, Sanyal M, Morozova O, Morimoto M, Elizondo LI, Bridgewater D, Lubieniecka J, Beirnes K, Myung C, Leung D, Fam HK, Choi K, Huang Y, Dionis KY, Zonana J, Keller K, Stenzel P, Mayfield C, Lücke T, Bokenkamp A, Marra MA, van Lohuizen M, Lewis DB, Shaw C, Boerkoel CF. Baradaran-Heravi A, et al. Among authors: fam hk. Hum Mol Genet. 2012 Jun 1;21(11):2572-87. doi: 10.1093/hmg/dds083. Epub 2012 Feb 28. Hum Mol Genet. 2012. PMID: 22378147 Free PMC article.