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Mitochondria, energetics, epigenetics, and cellular responses to stress.
Shaughnessy DT, McAllister K, Worth L, Haugen AC, Meyer JN, Domann FE, Van Houten B, Mostoslavsky R, Bultman SJ, Baccarelli AA, Begley TJ, Sobol RW, Hirschey MD, Ideker T, Santos JH, Copeland WC, Tice RR, Balshaw DM, Tyson FL. Shaughnessy DT, et al. Among authors: hirschey md. Environ Health Perspect. 2014 Dec;122(12):1271-8. doi: 10.1289/ehp.1408418. Epub 2014 Aug 15. Environ Health Perspect. 2014. PMID: 25127496 Free PMC article. Review.
Early-life mitochondrial DNA damage results in lifelong deficits in energy production mediated by redox signaling in Caenorhabditis elegans.
Hershberger KA, Rooney JP, Turner EA, Donoghue LJ, Bodhicharla R, Maurer LL, Ryde IT, Kim JJ, Joglekar R, Hibshman JD, Smith LL, Bhatt DP, Ilkayeva OR, Hirschey MD, Meyer JN. Hershberger KA, et al. Among authors: hirschey md. Redox Biol. 2021 Jul;43:102000. doi: 10.1016/j.redox.2021.102000. Epub 2021 May 5. Redox Biol. 2021. PMID: 33993056 Free PMC article.
Cellular energetics and mitochondrial uncoupling in canine aging.
Nicholatos JW, Robinette TM, Tata SVP, Yordy JD, Francisco AB, Platov M, Yeh TK, Ilkayeva OR, Huynh FK, Dokukin M, Volkov D, Weinstein MA, Boyko AR, Miller RA, Sokolov I, Hirschey MD, Libert S. Nicholatos JW, et al. Among authors: hirschey md. Geroscience. 2019 Apr;41(2):229-242. doi: 10.1007/s11357-019-00062-6. Epub 2019 Apr 1. Geroscience. 2019. PMID: 30937823 Free PMC article.
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.
Lombard DB, Alt FW, Cheng HL, Bunkenborg J, Streeper RS, Mostoslavsky R, Kim J, Yancopoulos G, Valenzuela D, Murphy A, Yang Y, Chen Y, Hirschey MD, Bronson RT, Haigis M, Guarente LP, Farese RV Jr, Weissman S, Verdin E, Schwer B. Lombard DB, et al. Among authors: hirschey md. Mol Cell Biol. 2007 Dec;27(24):8807-14. doi: 10.1128/MCB.01636-07. Epub 2007 Oct 8. Mol Cell Biol. 2007. PMID: 17923681 Free PMC article.
89 results