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From the covalent linkage of drugs to novel inhibitors of ribonucleotide reductase: synthesis and biological evaluation of valproic esters of 3'-C-methyladenosine.
Petrelli R, Meli M, Vita P, Torquati I, Ferro A, Vodnala M, D'Alessandro N, Tolomeo M, Del Bello F, Kusumanchi P, Franchetti P, Grifantini M, Jayaram HN, Hofer A, Cappellacci L. Petrelli R, et al. Among authors: del bello f. Bioorg Med Chem Lett. 2014 Nov 15;24(22):5304-9. doi: 10.1016/j.bmcl.2014.09.046. Epub 2014 Sep 28. Bioorg Med Chem Lett. 2014. PMID: 25304896
Dioxane and oxathiane nuclei: suitable substructures for muscarinic agonists.
Piergentili A, Quaglia W, Giannella M, Del Bello F, Bruni B, Buccioni M, Carrieri A, Ciattini S. Piergentili A, et al. Among authors: del bello f. Bioorg Med Chem. 2007 Jan 15;15(2):886-96. doi: 10.1016/j.bmc.2006.10.040. Epub 2006 Oct 21. Bioorg Med Chem. 2007. PMID: 17084634
Structure-activity relationships in 1,4-benzodioxan-related compounds. 9. From 1,4-benzodioxane to 1,4-dioxane ring as a promising template of novel alpha1D-adrenoreceptor antagonists, 5-HT1A full agonists, and cytotoxic agents.
Quaglia W, Piergentili A, Del Bello F, Farande Y, Giannella M, Pigini M, Rafaiani G, Carrieri A, Amantini C, Lucciarini R, Santoni G, Poggesi E, Leonardi A. Quaglia W, et al. Among authors: del bello f. J Med Chem. 2008 Oct 23;51(20):6359-70. doi: 10.1021/jm800461k. Epub 2008 Sep 26. J Med Chem. 2008. PMID: 18817363
Structure-activity relationships in 1,4-benzodioxan-related compounds. 10. Novel α1-adrenoreceptor antagonists related to openphendioxan: synthesis, biological evaluation, and α1d computational study.
Carrieri A, Piergentili A, Del Bello F, Giannella M, Pigini M, Leonardi A, Fanelli F, Quaglia W. Carrieri A, et al. Among authors: del bello f. Bioorg Med Chem. 2010 Oct 1;18(19):7065-77. doi: 10.1016/j.bmc.2010.08.002. Epub 2010 Aug 6. Bioorg Med Chem. 2010. PMID: 20801662
Might the observed α(2A)-adrenoreceptor agonism or antagonism of allyphenyline analogues be ascribed to different molecular conformations?
Diamanti E, Del Bello F, Carbonara G, Carrieri A, Fracchiolla G, Giannella M, Mammoli V, Piergentili A, Pohjanoksa K, Quaglia W, Scheinin M, Pigini M. Diamanti E, et al. Among authors: del bello f. Bioorg Med Chem. 2012 Mar 15;20(6):2082-90. doi: 10.1016/j.bmc.2012.01.035. Epub 2012 Jan 31. Bioorg Med Chem. 2012. PMID: 22341244
Favourable involvement of α2A-adrenoreceptor antagonism in the I₂-imidazoline binding sites-mediated morphine analgesia enhancement.
Mammoli V, Bonifazi A, Del Bello F, Diamanti E, Giannella M, Hudson AL, Mattioli L, Perfumi M, Piergentili A, Quaglia W, Titomanlio F, Pigini M. Mammoli V, et al. Among authors: del bello f. Bioorg Med Chem. 2012 Apr 1;20(7):2259-65. doi: 10.1016/j.bmc.2012.02.016. Epub 2012 Feb 13. Bioorg Med Chem. 2012. PMID: 22370341
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