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Nrf2 regulates ROS production by mitochondria and NADPH oxidase.
Kovac S, Angelova PR, Holmström KM, Zhang Y, Dinkova-Kostova AT, Abramov AY. Kovac S, et al. Among authors: zhang y. Biochim Biophys Acta. 2015 Apr;1850(4):794-801. doi: 10.1016/j.bbagen.2014.11.021. Epub 2014 Dec 5. Biochim Biophys Acta. 2015. PMID: 25484314 Free PMC article.
Electrophilic tuning of the chemoprotective natural product sulforaphane.
Ahn YH, Hwang Y, Liu H, Wang XJ, Zhang Y, Stephenson KK, Boronina TN, Cole RN, Dinkova-Kostova AT, Talalay P, Cole PA. Ahn YH, et al. Among authors: zhang y. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9590-5. doi: 10.1073/pnas.1004104107. Epub 2010 May 3. Proc Natl Acad Sci U S A. 2010. PMID: 20439747 Free PMC article.
An exceptionally potent inducer of cytoprotective enzymes: elucidation of the structural features that determine inducer potency and reactivity with Keap1.
Dinkova-Kostova AT, Talalay P, Sharkey J, Zhang Y, Holtzclaw WD, Wang XJ, David E, Schiavoni KH, Finlayson S, Mierke DF, Honda T. Dinkova-Kostova AT, et al. Among authors: zhang y. J Biol Chem. 2010 Oct 29;285(44):33747-55. doi: 10.1074/jbc.M110.163485. Epub 2010 Aug 26. J Biol Chem. 2010. PMID: 20801881 Free PMC article.
Nrf2 Activation Protects against Solar-Simulated Ultraviolet Radiation in Mice and Humans.
Knatko EV, Ibbotson SH, Zhang Y, Higgins M, Fahey JW, Talalay P, Dawe RS, Ferguson J, Huang JT, Clarke R, Zheng S, Saito A, Kalra S, Benedict AL, Honda T, Proby CM, Dinkova-Kostova AT. Knatko EV, et al. Among authors: zhang y. Cancer Prev Res (Phila). 2015 Jun;8(6):475-86. doi: 10.1158/1940-6207.CAPR-14-0362. Epub 2015 Mar 24. Cancer Prev Res (Phila). 2015. PMID: 25804610 Free PMC article.
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