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TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression.
Heyes E, Wilhelmson AS, Wenzel A, Manhart G, Eder T, Schuster MB, Rzepa E, Pundhir S, D'Altri T, Frank AK, Gentil C, Woessmann J, Schoof EM, Meggendorfer M, Schwaller J, Haferlach T, Grebien F, Porse BT. Heyes E, et al. Among authors: pundhir s. Nat Commun. 2023 Oct 4;14(1):6185. doi: 10.1038/s41467-023-41927-x. Nat Commun. 2023. PMID: 37794021 Free PMC article.
The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes.
Trempenau ML, Schuster MB, Pundhir S, Pereira MA, Kalvisa A, Tapia M, Su J, Ge Y, de Boer B, Balhuizen A, Bagger FO, Shliaha P, Sroczynska P, Walfridsson J, Grønbæk K, Theilgaard-Mönch K, Jensen ON, Helin K, Porse BT. Trempenau ML, et al. Among authors: pundhir s. Leukemia. 2023 Mar;37(3):593-605. doi: 10.1038/s41375-023-01810-6. Epub 2023 Jan 12. Leukemia. 2023. PMID: 36631623 Free PMC article.
Transcription factor-driven coordination of cell cycle exit and lineage-specification in vivo during granulocytic differentiation : In memoriam Professor Niels Borregaard.
Theilgaard-Mönch K, Pundhir S, Reckzeh K, Su J, Tapia M, Furtwängler B, Jendholm J, Jakobsen JS, Hasemann MS, Knudsen KJ, Cowland JB, Fossum A, Schoof E, Schuster MB, Porse BT. Theilgaard-Mönch K, et al. Among authors: pundhir s. Nat Commun. 2022 Jun 23;13(1):3595. doi: 10.1038/s41467-022-31332-1. Nat Commun. 2022. PMID: 35739121 Free PMC article.
PTBP1 promotes hematopoietic stem cell maintenance and red blood cell development by ensuring sufficient availability of ribosomal constituents.
Rehn M, Wenzel A, Frank AK, Schuster MB, Pundhir S, Jørgensen N, Vitting-Seerup K, Ge Y, Jendholm J, Michaut M, Schoof EM, Jensen TL, Rapin N, Sapio RT, Andersen KL, Lund AH, Solimena M, Holzenberger M, Pestov DG, Porse BT. Rehn M, et al. Among authors: pundhir s. Cell Rep. 2022 May 10;39(6):110793. doi: 10.1016/j.celrep.2022.110793. Cell Rep. 2022. PMID: 35545054 Free article.
Epigenetic and Transcriptomic Characterization of Pure Adipocyte Fractions From Obese Pigs Identifies Candidate Pathways Controlling Metabolism.
Jacobsen MJ, Havgaard JH, Anthon C, Mentzel CMJ, Cirera S, Krogh PM, Pundhir S, Karlskov-Mortensen P, Bruun CS, Lesnik P, Guerin M, Gorodkin J, Jørgensen CB, Fredholm M, Barrès R. Jacobsen MJ, et al. Among authors: pundhir s. Front Genet. 2019 Dec 17;10:1268. doi: 10.3389/fgene.2019.01268. eCollection 2019. Front Genet. 2019. PMID: 31921306 Free PMC article.
Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML.
Jakobsen JS, Laursen LG, Schuster MB, Pundhir S, Schoof E, Ge Y, d'Altri T, Vitting-Seerup K, Rapin N, Gentil C, Jendholm J, Theilgaard-Mönch K, Reckzeh K, Bullinger L, Döhner K, Hokland P, Fitzgibbon J, Porse BT. Jakobsen JS, et al. Among authors: pundhir s. Sci Adv. 2019 Jul 10;5(7):eaaw4304. doi: 10.1126/sciadv.aaw4304. eCollection 2019 Jul. Sci Adv. 2019. PMID: 31309149 Free PMC article.
24 results