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Telomerase mutations in smokers with severe emphysema.
Stanley SE, Chen JJ, Podlevsky JD, Alder JK, Hansel NN, Mathias RA, Qi X, Rafaels NM, Wise RA, Silverman EK, Barnes KC, Armanios M. Stanley SE, et al. J Clin Invest. 2015 Feb;125(2):563-70. doi: 10.1172/JCI78554. Epub 2014 Dec 22. J Clin Invest. 2015. PMID: 25562321 Free PMC article. Clinical Trial.
Diagnostic utility of telomere length testing in a hospital-based setting.
Alder JK, Hanumanthu VS, Strong MA, DeZern AE, Stanley SE, Takemoto CM, Danilova L, Applegate CD, Bolton SG, Mohr DW, Brodsky RA, Casella JF, Greider CW, Jackson JB, Armanios M. Alder JK, et al. Among authors: stanley se. Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2358-E2365. doi: 10.1073/pnas.1720427115. Epub 2018 Feb 20. Proc Natl Acad Sci U S A. 2018. PMID: 29463756 Free PMC article.
Short telomeres: a repeat offender in IPF.
Stanley SE, Armanios M. Stanley SE, et al. Lancet Respir Med. 2014 Jul;2(7):513-4. doi: 10.1016/S2213-2600(14)70140-7. Epub 2014 Jun 24. Lancet Respir Med. 2014. PMID: 24973280 No abstract available.
Telomere dysfunction causes alveolar stem cell failure.
Alder JK, Barkauskas CE, Limjunyawong N, Stanley SE, Kembou F, Tuder RM, Hogan BL, Mitzner W, Armanios M. Alder JK, et al. Among authors: stanley se. Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5099-104. doi: 10.1073/pnas.1504780112. Epub 2015 Apr 3. Proc Natl Acad Sci U S A. 2015. PMID: 25840590 Free PMC article.
ZCCHC8, the nuclear exosome targeting component, is mutated in familial pulmonary fibrosis and is required for telomerase RNA maturation.
Gable DL, Gaysinskaya V, Atik CC, Talbot CC Jr, Kang B, Stanley SE, Pugh EW, Amat-Codina N, Schenk KM, Arcasoy MO, Brayton C, Florea L, Armanios M. Gable DL, et al. Among authors: stanley se. Genes Dev. 2019 Oct 1;33(19-20):1381-1396. doi: 10.1101/gad.326785.119. Epub 2019 Sep 5. Genes Dev. 2019. PMID: 31488579 Free PMC article.
43 results