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Contact sensitizers trigger human CD1-autoreactive T-cell responses.
Betts RJ, Perkovic A, Mahapatra S, Del Bufalo A, Camara K, Howell AR, Martinozzi Teissier S, De Libero G, Mori L. Betts RJ, et al. Among authors: howell ar. Eur J Immunol. 2017 Jul;47(7):1171-1180. doi: 10.1002/eji.201746939. Epub 2017 May 23. Eur J Immunol. 2017. PMID: 28440548 Free PMC article.
ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth.
Remsberg JR, Suciu RM, Zambetti NA, Hanigan TW, Firestone AJ, Inguva A, Long A, Ngo N, Lum KM, Henry CL, Richardson SK, Predovic M, Huang B, Dix MM, Howell AR, Niphakis MJ, Shannon K, Cravatt BF. Remsberg JR, et al. Among authors: howell ar. Nat Chem Biol. 2021 Aug;17(8):856-864. doi: 10.1038/s41589-021-00785-8. Epub 2021 Apr 29. Nat Chem Biol. 2021. PMID: 33927411 Free PMC article.
Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae.
Chandra S, Gray J, Kiosses WB, Khurana A, Hitomi K, Crosby CM, Chawla A, Fu Z, Zhao M, Veerapen N, Richardson SK, Porcelli SA, Besra G, Howell AR, Sharma S, Peters B, Kronenberg M. Chandra S, et al. Among authors: howell ar. Nat Commun. 2018 Oct 15;9(1):4279. doi: 10.1038/s41467-018-06646-8. Nat Commun. 2018. PMID: 30323255 Free PMC article.
Amide-Linked C4″-Saccharide Modification of KRN7000 Provides Potent Stimulation of Human Invariant NKT Cells and Anti-Tumor Immunity in a Humanized Mouse Model.
Saavedra-Avila NA, Keshipeddy S, Guberman-Pfeffer MJ, Pérez-Gallegos A, Saini NK, Schäfer C, Carreño LJ, Gascón JA, Porcelli SA, Howell AR. Saavedra-Avila NA, et al. Among authors: howell ar. ACS Chem Biol. 2020 Dec 18;15(12):3176-3186. doi: 10.1021/acschembio.0c00707. Epub 2020 Dec 9. ACS Chem Biol. 2020. PMID: 33296161 Free PMC article.
Glycolipids that elicit IFN-γ-biased responses from natural killer T cells.
Tyznik AJ, Farber E, Girardi E, Birkholz A, Li Y, Chitale S, So R, Arora P, Khurana A, Wang J, Porcelli SA, Zajonc DM, Kronenberg M, Howell AR. Tyznik AJ, et al. Among authors: howell ar. Chem Biol. 2011 Dec 23;18(12):1620-30. doi: 10.1016/j.chembiol.2011.10.015. Chem Biol. 2011. PMID: 22195564 Free PMC article.
82 results