Espinosa JM - Search Results

1

p53 Family Members Regulate Phenotypic Response to Aurora Kinase A Inhibition in Triple-Negative Breast Cancer.

Tentler JJ, Ionkina AA, Tan AC, Newton TP, Pitts TM, Glogowska MJ, Kabos P, Sartorius CA, Sullivan KD, Espinosa JM, Eckhardt SG, Diamond JR. Tentler JJ, et al. Among authors: espinosa jm. Mol Cancer Ther. 2015 May;14(5):1117-29. doi: 10.1158/1535-7163.MCT-14-0538-T. Epub 2015 Mar 10. Mol Cancer Ther. 2015. PMID: 25758253 Free PMC article.

2

CDK8 is a stimulus-specific positive coregulator of p53 target genes.

Donner AJ, Szostek S, Hoover JM, Espinosa JM. Donner AJ, et al. Among authors: espinosa jm. Mol Cell. 2007 Jul 6;27(1):121-33. doi: 10.1016/j.molcel.2007.05.026. Mol Cell. 2007. PMID: 17612495 Free PMC article.

3

Mechanisms of regulatory diversity within the p53 transcriptional network.

Espinosa JM. Espinosa JM. Oncogene. 2008 Jul 3;27(29):4013-23. doi: 10.1038/onc.2008.37. Epub 2008 Feb 18. Oncogene. 2008. PMID: 18278067 Free PMC article.

4

The p53 circuit board.

Sullivan KD, Gallant-Behm CL, Henry RE, Fraikin JL, Espinosa JM. Sullivan KD, et al. Among authors: espinosa jm. Biochim Biophys Acta. 2012 Apr;1825(2):229-44. doi: 10.1016/j.bbcan.2012.01.004. Epub 2012 Feb 7. Biochim Biophys Acta. 2012. PMID: 22333261 Free PMC article. Review.

5

ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53.

Sullivan KD, Padilla-Just N, Henry RE, Porter CC, Kim J, Tentler JJ, Eckhardt SG, Tan AC, DeGregori J, Espinosa JM. Sullivan KD, et al. Among authors: espinosa jm. Nat Chem Biol. 2012 Jul;8(7):646-54. doi: 10.1038/nchembio.965. Epub 2012 Jun 3. Nat Chem Biol. 2012. PMID: 22660439 Free PMC article.

6

A genetic screen identifies TCF3/E2A and TRIAP1 as pathway-specific regulators of the cellular response to p53 activation.

Andrysik Z, Kim J, Tan AC, Espinosa JM. Andrysik Z, et al. Among authors: espinosa jm. Cell Rep. 2013 May 30;3(5):1346-54. doi: 10.1016/j.celrep.2013.04.014. Epub 2013 May 16. Cell Rep. 2013. PMID: 23684607 Free PMC article.

7

Tumor suppression by p53: is apoptosis important or not?

Mellert H, Espinosa JM. Mellert H, et al. Among authors: espinosa jm. Cell Rep. 2013 May 30;3(5):1335-6. doi: 10.1016/j.celrep.2013.05.011. Cell Rep. 2013. PMID: 23726020 Free article.

8

Inhibition of telomerase recruitment and cancer cell death.

Nakashima M, Nandakumar J, Sullivan KD, Espinosa JM, Cech TR. Nakashima M, et al. Among authors: espinosa jm. J Biol Chem. 2013 Nov 15;288(46):33171-80. doi: 10.1074/jbc.M113.518175. Epub 2013 Oct 4. J Biol Chem. 2013. PMID: 24097987 Free PMC article.

9

Back to bases: how a nucleotide biosynthetic enzyme controls p53 activation.

Guarnieri AL, Espinosa JM. Guarnieri AL, et al. Among authors: espinosa jm. Mol Cell. 2014 Feb 6;53(3):365-7. doi: 10.1016/j.molcel.2014.01.025. Mol Cell. 2014. PMID: 24507714 Free PMC article.

10

Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms.

Allen MA, Andrysik Z, Dengler VL, Mellert HS, Guarnieri A, Freeman JA, Sullivan KD, Galbraith MD, Luo X, Kraus WL, Dowell RD, Espinosa JM. Allen MA, et al. Among authors: espinosa jm. Elife. 2014 May 27;3:e02200. doi: 10.7554/eLife.02200. Elife. 2014. PMID: 24867637 Free PMC article.

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