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Orchestrating the biosynthesis of an unnatural pyrrolysine amino Acid for its direct incorporation into proteins inside living cells.
Chemistry. 2015 May 18;21(21):7701-4. doi: 10.1002/chem.201500971. Epub 2015 Apr 2.
Chemistry. 2015.
PMID: 25845346
Synthesis of ε-N-propionyl-, ε-N-butyryl-, and ε-N-crotonyl-lysine containing histone H3 using the pyrrolysine system.
Gattner MJ, Vrabel M, Carell T.
Gattner MJ, et al.
Chem Commun (Camb). 2013 Jan 14;49(4):379-81. doi: 10.1039/c2cc37836a. Epub 2012 Nov 28.
Chem Commun (Camb). 2013.
PMID: 23192406
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Norbornenes in inverse electron-demand Diels-Alder reactions.
Vrabel M, Kölle P, Brunner KM, Gattner MJ, López-Carrillo V, de Vivie-Riedle R, Carell T.
Vrabel M, et al. Among authors: gattner mj.
Chemistry. 2013 Sep 27;19(40):13309-12. doi: 10.1002/chem.201301838. Epub 2013 Sep 11.
Chemistry. 2013.
PMID: 24027163
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Structural insights into incorporation of norbornene amino acids for click modification of proteins.
Schneider S, Gattner MJ, Vrabel M, Flügel V, López-Carrillo V, Prill S, Carell T.
Schneider S, et al. Among authors: gattner mj.
Chembiochem. 2013 Nov 4;14(16):2114-8. doi: 10.1002/cbic.201300435. Epub 2013 Sep 11.
Chembiochem. 2013.
PMID: 24027216
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Sulfonyl azide-mediated norbornene aziridination for orthogonal peptide and protein labeling.
Gattner MJ, Ehrlich M, Vrabel M.
Gattner MJ, et al.
Chem Commun (Camb). 2014 Oct 25;50(83):12568-71. doi: 10.1039/c4cc04117h.
Chem Commun (Camb). 2014.
PMID: 25198620
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Genetically designed biomolecular capping system for mesoporous silica nanoparticles enables receptor-mediated cell uptake and controlled drug release.
Datz S, Argyo C, Gattner M, Weiss V, Brunner K, Bretzler J, von Schirnding C, Torrano AA, Spada F, Vrabel M, Engelke H, Bräuchle C, Carell T, Bein T.
Datz S, et al.
Nanoscale. 2016 Apr 21;8(15):8101-10. doi: 10.1039/c5nr08163g.
Nanoscale. 2016.
PMID: 27021414
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The radical SAM enzyme AlbA catalyzes thioether bond formation in subtilosin A.
Flühe L, Knappe TA, Gattner MJ, Schäfer A, Burghaus O, Linne U, Marahiel MA.
Flühe L, et al. Among authors: gattner mj.
Nat Chem Biol. 2012 Feb 26;8(4):350-7. doi: 10.1038/nchembio.798.
Nat Chem Biol. 2012.
PMID: 22366720
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Discovery of ABBV-154, an anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody-Drug Conjugate (iADC).
Hobson AD, Xu J, Welch DS, Marvin CC, McPherson MJ, Gates B, Liao X, Hollmann M, Gattner MJ, Dzeyk K, Sarvaiya H, Shenoy VM, Fettis MM, Bischoff AK, Wang L, Santora LC, Wang L, Fitzgibbons J, Salomon P, Hernandez A Jr, Jia Y, Goess CA, Mathieu SL, Bryant SH, Larsen ME, Cui B, Tian Y.
Hobson AD, et al. Among authors: gattner mj.
J Med Chem. 2023 Sep 14;66(17):12544-12558. doi: 10.1021/acs.jmedchem.3c01174. Epub 2023 Sep 1.
J Med Chem. 2023.
PMID: 37656698
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