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A modular toolkit to inhibit proline-rich motif-mediated protein-protein interactions.
Opitz R, Müller M, Reuter C, Barone M, Soicke A, Roske Y, Piotukh K, Huy P, Beerbaum M, Wiesner B, Beyermann M, Schmieder P, Freund C, Volkmer R, Oschkinat H, Schmalz HG, Kühne R. Opitz R, et al. Among authors: schmalz hg. Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5011-6. doi: 10.1073/pnas.1422054112. Epub 2015 Apr 6. Proc Natl Acad Sci U S A. 2015. PMID: 25848013 Free PMC article.
Addressing protein-protein interactions with small molecules: a Pro-Pro dipeptide mimic with a PPII helix conformation as a module for the synthesis of PRD-binding ligands.
Zaminer J, Brockmann C, Huy P, Opitz R, Reuter C, Beyermann M, Freund C, Müller M, Oschkinat H, Kühne R, Schmalz HG. Zaminer J, et al. Among authors: schmalz hg. Angew Chem Int Ed Engl. 2010 Sep 17;49(39):7111-5. doi: 10.1002/anie.201001739. Angew Chem Int Ed Engl. 2010. PMID: 20803590 No abstract available.
Potassium (1-methoxy-carbonyl-2-methyl-prop-2-en-2-yl-idene)azinate.
Reuter C, Neudörfl JM, Schmalz HG. Reuter C, et al. Among authors: schmalz hg. Acta Crystallogr Sect E Struct Rep Online. 2010 Mar 27;66(Pt 4):m461. doi: 10.1107/S1600536810010159. Acta Crystallogr Sect E Struct Rep Online. 2010. PMID: 21580546 Free PMC article.
115 results