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REGγ is critical for skin carcinogenesis by modulating the Wnt/β-catenin pathway.
Li L, Dang Y, Zhang J, Yan W, Zhai W, Chen H, Li K, Tong L, Gao X, Amjad A, Ji L, Jing T, Jiang Z, Shi K, Yao L, Song D, Liu T, Yang X, Yang C, Cai X, Xu W, Huang Q, He J, Liu J, Chen T, Moses RE, Fu J, Xiao J, Li X. Li L, et al. Among authors: chen t, chen h. Nat Commun. 2015 Apr 24;6:6875. doi: 10.1038/ncomms7875. Nat Commun. 2015. PMID: 25908095 Free article.
REGγ accelerates melanoma formation by regulating Wnt/β-catenin signalling pathway.
Chen H, Gao X, Sun Z, Wang Q, Zuo D, Pan L, Li K, Chen J, Chen G, Hu K, Li K, Shah AS, Huang T, Muhammad Zeeshan B, Tong L, Jiao C, Liu J, Chen T, Yao L, Dang Y, Liu T, Li L. Chen H, et al. Among authors: chen j, chen t, chen g. Exp Dermatol. 2017 Nov;26(11):1118-1124. doi: 10.1111/exd.13394. Epub 2017 Aug 30. Exp Dermatol. 2017. PMID: 28605165
Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction.
Liu X, Wang Y, Lu H, Li J, Yan X, Xiao M, Hao J, Alekseev A, Khong H, Chen T, Huang R, Wu J, Zhao Q, Wu Q, Xu S, Wang X, Jin W, Yu S, Wang Y, Wei L, Wang A, Zhong B, Ni L, Liu X, Nurieva R, Ye L, Tian Q, Bian XW, Dong C. Liu X, et al. Among authors: chen t. Nature. 2019 Mar;567(7749):525-529. doi: 10.1038/s41586-019-0979-8. Epub 2019 Feb 27. Nature. 2019. PMID: 30814730 Free PMC article.
TransVar: a multilevel variant annotator for precision genomics.
Zhou W, Chen T, Chong Z, Rohrdanz MA, Melott JM, Wakefield C, Zeng J, Weinstein JN, Meric-Bernstam F, Mills GB, Chen K. Zhou W, et al. Among authors: chen k, chen t. Nat Methods. 2015 Nov;12(11):1002-3. doi: 10.1038/nmeth.3622. Nat Methods. 2015. PMID: 26513549 Free PMC article. No abstract available.
novoBreak: local assembly for breakpoint detection in cancer genomes.
Chong Z, Ruan J, Gao M, Zhou W, Chen T, Fan X, Ding L, Lee AY, Boutros P, Chen J, Chen K. Chong Z, et al. Among authors: chen j, chen k, chen t. Nat Methods. 2017 Jan;14(1):65-67. doi: 10.1038/nmeth.4084. Epub 2016 Nov 28. Nat Methods. 2017. PMID: 27892959 Free PMC article.
ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis.
Liu J, Cho SN, Akkanti B, Jin N, Mao J, Long W, Chen T, Zhang Y, Tang X, Wistub II, Creighton CJ, Kheradmand F, DeMayo FJ. Liu J, et al. Among authors: chen t. Cell Rep. 2015 Mar 10;10(9):1599-1613. doi: 10.1016/j.celrep.2015.02.014. Epub 2015 Mar 5. Cell Rep. 2015. PMID: 25753424 Free PMC article.
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